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QUESTION 34 The gene encoding an E. coli tRNA containing the anticodon 5-GUA-3 mutates so that the anticodon now is 5-UUA-

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a) is the right option. This mutation is a nonsense mutation type. In the mRNA 5'UAC3' codes for tyrosine amino acid which anticodon in tRNA is 5'GUA3'. Due to nonsense mutation tRNA anticodon 5'GUA3' change to 5'UAA3' which are stop codon. So, when mRNA comes to pair with tRNA anticodon it read as stop codon and translation gets to stop. In the nonsense mutation a truncated, incomplete, and usually nonfunctional protein product form.

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