Dendrotoxins, produced by the mamba snake, are inhibitors of the voltage-gated K+ channels. What phase of the action potential would this toxin affect? How would it affect ion permeability during this phase? How would ion movement be affected?
Dendrotoxins are type of the neurotoxins which block voltage gated potassium channales which enhances the production o fthe acteyl choline in the neuromuscular junction . It act at the resting memberane potential where the cell will be repolarizing the memberane , it produces the prolonged duration o fthe action potentials which results in the hyperexcitibilty and convulsive symptoms
Dendrotoxins, produced by the mamba snake, are inhibitors of the voltage-gated K+ channels. What phase of...
choices for A: Na+/K+ pumps, voltage gated K+ channels,
voltage gated Ca+ channels, voltage gated Na+ channels
choices for B: bidirectionally, unidirectionally
choices for C: Na+/K+ pumps, voltage gated K+ channels,
voltage gated Ca+ channels, voltage gated Na+ channels
choices for D: Na+/K+ pumps, voltage gated K+ channels,
voltage gated Ca+ channels, voltage gated Na+ channels
Consider this graph illustrating the generation of an action potential across the plasma membrane of a stimulated neuron. +40 ACTION POTENTIAL plasma membrane potential...
3. Many neurons contain "delayed K channels". Like voltage-gated Nat channels, these voltage-gated K+ channels open in response to a rise in membrane potential and then undergo inactivation. However, opening of the voltage-gated K channels lags behind opening of the voltage-gated Na channels. a) Why does neuronal function require the voltage-gated K channels to open more slowly than the voltage-gated Na channels? b) Compared to a neuron that lacks voltage-gated K channels, what differences would you expect in the shape...
Conotoxin is produced by marine cone snails. Among its effects is to block voltage-gated Ca2+ channels in neurons. A. What anatomical part of a neuron would be affected by conotoxin? B. How would the neuron’s action potential be affected by conotoxin? Explain, using at least TWO of the following terms: threshold, depolarization, repolarization, hyperpolarization, summation, IPSP, EPSP, exocytosis C. If conotoxin affected a somatic motor neuron, would this toxin cause muscle weakness or increased muscle tension? Explain why.
The plateau phase of the ventricular action potential is caused by O fast voltage-gated Ca2+ channels opening fast Nachannels opening O slow K* channels opening Oslow voltage-gated Ca2+ channels opening Submit Request Answer
1. What triggers the opening of each of the different channels: ligand-gated K+ channels, ligand-gated Na+ channels, ligand-gated Cl- channels, voltage-gated Na+ channels, voltage-gated K+ channels, voltage-gated Ca2+ channels. 2. What happens to membrane potential in the immediate area where the channel is located when the channel opens and ions flow through? 3. Since graded and action potentials happen in different locations on the neuron, explain what has to happen to link these different events together.
Compare the roles that Na+-gated and K+-gated ion channels play in an action potential.
For each phase of an action potential, indicate the ion channel most responsible for the membrane potential change that occurs during the phase. Action Potential Phases Ion Channels Depolarization phase Repolarization phase Hyperpolarization phase Voltage-gated potassium channels Chemically-gated sodium channels Chemically-gated potassium channels Voltage-gated sodium channels
Assume a mutation of the gene coding for the voltage-gated sodium channel resulted in channels that do not have the ball and chain part of the protein. Which of the following would you expect to see? a. A change in the ion selectivity of the channel of the mutated channels, allowing ions other than sodium to move through it. b. A change in the voltage sensitivity of the channel so that it does not open until more depolarized voltages. c....
How would you alter sodium and/or potassium voltage-gated channels to preserve their dependence on voltage, but eliminate action potentials? Effect of altering Na/K channels
You are studying the permeability on Voltage-Gated Sodium Channels involved in action potential generation. Predict what would happen to the permeability of Sodium in the following cases (would it decrease, increase or stay the same?). Explain why you chose your answer. i.Increased receptor number. ii. Add a drug that make channel stay open longer. iii. Raise Vm above+35mV. iv.Lower Vm below -70mV. v.Add a drug that prevents channel opening. vi. Add more Na+ to the extracellular environment.