Categorize the groups attached to the ring in salicylamide as activators, deactivators, ortho/para directors, or meta directors. Predict the product(s) of the reaction.
Categorize the groups attached to the ring in salicylamide as activators, deactivators, ortho/para directors, or meta directors. Predict the product(s) of the reaction .
Classify each substituent as ortho, para activators; ortho, para deactivators; or meta deactivators. ortho, para activators ortho, para deactivators meta deactivators CHO COon NH2 C(CH3)a
4. Predict the major product for the following reaction. Cly/AICI, OH 5. Predict the major product for the following reaction. OCH, HNO/H2SO4 OCH 6. Discuss ortho, meta para directors, activators and deactivators and predict products. De 9 © PL
Are these groups activating or deactivating, ortho/para or meta directors? Table 2 EAS data and results. Compound Structure of the Compound ЗаliИТА 0 ОТАРІЯ Activating Ortho/para or Deactivating Or meta director Toluene Aniline Phenyl Acetate Acetanilide Anisole OCHZ slom 2A Methyl Benzoate ctly Acetophenone Benzaldehyde Yяонт abilind Chlorobenzene (agasi. q. sb): A
Objectives - Section 1 • Identify a substituent as an ortho para director or a meta director, Draw the resonance structure that explains the relative directing ability of a specific substituent. Classify a substituent as an activating or a deactivating group. Explain why the halogens are ortho/para directors but are deactivators. • 1. Draw the mechanism of the reaction below and use resonance structures of the arenium ion intermediate to explain why the starting material is an ortho/para director
Label the following as activating (A) or deactivating (D), and then also as ortho/para directors (OP) or meta directors (M). Write the answer below each group. N "Here with other ty A/D? = = = = OP/M? = f) Using resonance structures, explain why a nitro group is "meta-directing" (i.e. does the nitro group actually affect the meta positions?) g) As mentioned in class, the halogens are a bit anomalous as substituents on the aromatic ring: they are deactivating groups,...
5. All electron-donating groups are activating groups and all are ortho-para directors with the exception of substituents, all electron-withdrawing groups are deactivating groups and all are meta directors. A. hydroxyl B. amino C. halogens D. alkoxyl 6. Hydrogen abstraction from the methyl group of methylbenzene (toluene) produces a radical called the radical. A. allylic B. free C. halogen D. benzyllic 7. The stability of benzyllic radicals can be explained by theory. A. resonance B. bond order C. inductive D. molecular...
Predict the effect the substituent attached to the benzene ring below would have on electrophilic aromatic substitution reactions? CH, CH3 a) meta director, deactivator b) ortho/para director, activator c) meta director, activator d) ortho/para director, deactivator
437 Predict whether the following substituents on the benzene ring are likely to be ha para directing or meta directing and whether they are like to be ring activating or ring deactivating deact vabang a) - NH(CH 4.38 For each of the monosabstituted benenes shown below, (1) Indicate whether the substituent is ortho, para directing or meta directing (2) Draw the structure of the main monosubstitution product for each of the reactions indicated orth. OCH3 + HCl -OCHE (fecutulys ortho...
15. Indicate those ortho/para director(s) and those meta director(s) - NO2 Br - -C₂Hs - NH2 CoHs nat reagent(s), solvent(s) and chemicals are needed in making a Grignard reagent (C2HsMgBri? Choose from the following list. Water diethyl ether lithium, phenyl bromide, ethyl bromide (MR) iodine, sodium bromide, heat 17. Which one of the following reaction is a nucleophilic aromatic substitution reaction? Which one is an electrophilic aromatic substitution? HNOH,SO 18. Predict the product:
The NMR spectrum suggests the formation of the meta-substituted product, but NH2 is an ortho/para directing group. Using the given chemicals, provide a mechanism to arrive at the meta-substituted product. 5. Adam Splidda and Flo Wrene were asked to make 4-aminobenzenesulfonic acid. They came up with the plan below. The Plan: NH2 SO3 NH2 H2SO4 HO3S 4-aminobenzenesulfonic acid The product: S, 1H t, 1H s, 2H d d, 1H 1H s, 1H 0 4 PPM Were they successful? Draw the...