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In looking through sequence information from the first assignment, you may have noticed there was no...

In looking through sequence information from the first assignment, you may have noticed there was no ONE TRUE SEQUENCE, and that there were quite a few ways to present the information with different databases and multiple entries for each database. Of most importance to us right now is understanding why it matters if the sequence being described is genomic or if it was an mRNA - and if it was an mRNA – was it a splice-site variant.

A) What’s the difference between a genomic sequence and an mRNA? Does this apply to prokaryotes and eukaryotes equally?

B) What is a splice-site variant of a gene? How can the same genomic sequence code for multiple different mRNAs that do not have the same coding region and may even have different start and stop sites?

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