Question

You are checking how different molecules affect gene expression. Based on the data below, write what kind of genes might be affected by the molecules and what could be the role of each molecule…

Molecule Effect when present Effect when absent

A 4 proteins are produced in normal quantity No proteins are produced no matter which other molecules we add

B No proteins are produced (or in extremely small quantity) 4 proteins are produced in normal quantity – if A is present

C 4 proteins are produced in large quantities if D and E are present 4 proteins are produced in normal quantity – if A is present

D 4 proteins are produced in large quantities if C and E are present 4 proteins are produced in normal quantity – if A is present

E 4 proteins are produced in large quantities if C and D are present 4 proteins are produced in normal quantity – if A is present

F No proteins are produced (or in extremely small quantity) if C is present 4 proteins are produced in normal quantity – if A is present

Answer 1

Molecule A is RNA polymerase, which binds to Prometer of the legenes (presumably a rigene oporon) and caused basal level transcription. without RNA pol, No transcription is possible with any other. Protein Molecule B is a repressor of this operan, that binds some regulatory region or operator region of this operon and represses transcription Absence causes basal level transcription en presence of RNA pol. - Molecul C, D, E are all co-activators that bind. together to an enhancer sequence near this. operon and causes high level transcription. All three are needed for this function and excepts neither work the other two. Their absence causes basal level transcription by RNA Polo Malecule facts as a repressar in presence of molecule c.. They bind to the operator region together and repress transcription.