Question

2. A lethal recessive condition is responsible for the death of 1 out of every 10,000 babies born in the United States. p2+2pq 1) P of dominantallele contaol led by a of ecessive allele,J par aldes a. Assuming HWE, what is the frequency 8f homowgo individuals in the population? 2 10.0001 10,000 b. Assuming HWE, what is the frequency of the recessive allele in the population? 2 0 0001 do ooo1 2 o-0001 0.01. 0.01 c. Do you think this gene would actually be in HWE in this population? Why or why not?
can someone please help me with the question “c” asap with an explanation please.

Answer 1

Ans - Since you have found

q=0.01

since the equation is of HWE is

p^2 + 2pq + q^2 = 1

now q=0.01 we will find p

Since according to HWE (p+q)^2 =1

so squaring on both sides

p + q = 1

p + 0.01 = 1

p = 1-0.01

p= 0.99

Now if p and q satisfies the HWE then.its is actually in population.

(0.99)^2 + 2×0.99×0.01 + (0.01)^2

on calculating above we get this equals to 1

Hence the above gene is actually present in the HWE in this population.