Homework Answers
16.
if a miRNA binds to a target mRNA sequence with exact complementariry, it will result in the direct degradation of the mRNA; however, if the miRNA binds with partial complementarity gene-silencing and inhibition of translation will occur.
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16. If a miRNA binds to a target mRNA sequence with exact complementarity, it will result...
Q.10 [5marks] Explain the two distinct functional outcomes for a mRNA when a miRNA/RISC complex binds...
Q.10 [5marks] Explain the two distinct functional outcomes for a mRNA when a miRNA/RISC complex binds to its 3' UTR.
In eukaryotes, miR-5 is a microRNA with sequence complementarity to the 3 UTR of the mRNA...
In eukaryotes, miR-5 is a microRNA with sequence complementarity to the 3 UTR of the mRNA transcript encoded by the UCD gene. The UCD gene encodes for a protein that acts as an allosteric activator of the protein p101. The p101 protein is a histone acetyl transferase (HAT) which is an enzyme that acetylates histones when the protein is in its active form A different lung cancer cell line is found to have significantly decreased amounts of histone acetylation. Which...
1 a. Which prokaryotic ribosomal subunit binds the mRNA? b. What is the sequence in the...
1 a. Which prokaryotic ribosomal subunit binds the mRNA? b. What is the sequence in the mRNA called that facilitates this interaction, and where is it located? c. Which specific component within this particular subunit facilitates binding to the mRNA?
In eukaryotes, miR-5 is a microRNA with sequence complementarity to the 3 UTR of the mRNA...
In eukaryotes, miR-5 is a microRNA with sequence complementarity to the 3 UTR of the mRNA transcript encoded by the UCD gene. The UCD gene encodes for a protein that acts as an allosteric activator of the protein p101. The p101 protein is a histone acetyl transferase (HAT) which is an enzyme that acetylates histones when the protein is in its active form In a lung cancer cell line, the p101 protein is overly active leading to misregulation of gene...
Question: In eukaryotes, miR-5 is a microRNA with sequence complementarity to the 3’UTR of the mRNA...
Question: In eukaryotes, miR-5 is a microRNA with sequence complementarity to the 3’UTR of the mRNA transcript encoded by the ABC gene. The ABC gene encodes for a protein that acts as an allosteric activator of the protein p101. The p101 protein is a histone acetyl transferase (HAT) which is an enzyme that acetylates histones when the protein is in its active form. A. In a lung cancer cell line, the p101 protein is overly active leading to misregulation of...
Which of the following statements regarding the TATA binding protein (TBP) are true: Recognizes a sequence...
Which of the following statements regarding the TATA binding protein (TBP) are true: Recognizes a sequence that is similar are identical to 5'TATAAA3' Ο Ο Ο All are correct. It is considered a universal transcription factor It is a part of TEIID protein complex It binds to a consensus sequence The backbone of a DNA molecule is made up of phosphate groups made up of sugars made up of alternating phosphate and sugar groups Made up of alternating sugars and...
BONUS (10 points, 2 points each): Given below is a sequence of mRNA that is transcribed...
BONUS (10 points, 2 points each): Given below is a sequence of mRNA that is transcribed from a structural and mRNA: AUG CGC GOA UCC CCC ACC AGA ACG GAX UGA-3 G-C 1. Using the codon chart provided below, write down the predicted amino acid sequence of the protein the produced from this mRNA 3-UAC GCG EXU AGG GGG UGG UCU UGC COU 2). Write down the DNA sequence of the structural pene from which this mRNA sequence is transcribed...
If mRNA is mispliced and what was once an intron now becomes coding sequence, what may...
If mRNA is mispliced and what was once an intron now becomes coding sequence, what may happen? A. Will always have frameshift that will cause the appearance of new stop codons. B. New coding sequence could be spliced in-frame, could result in new amino acids and proteins C. Misplicing of mRNA can never occur D. None Above
5. ZBP1 binds mRNAs. How would you determine whether there is a specific sequence in the...
5. ZBP1 binds mRNAs. How would you determine whether there is a specific sequence in the mRNA that is required for ZBP1 binding? (Hint: they discuss relevant techniques at the bottom of page 1899 in the article, but make sure you use your own words in your answer). (5 points)
1)A particular combination of SNPs on a chromosome that are inherited together are called a ??...
1)A particular combination of SNPs on a chromosome that are inherited together are called a ?? 2)During interphase, irregularly shaped nuclear structures that contain rDNA clusters are called ?? 3)____________are non-functional genes that have a sequence similarity to a gene family 4) If incorrect splicing occurs due to RNA sequences that closely resemble a real splice site, it is called_____________ splice site selection?? 5) The histones are highly acidic proteins that interact with positively charged DNA. Group of answer choices----...
In eukaryotes, miR-5 is a microRNA with sequence complementarity to the 3 UTR of the mRNA transcript encoded by the UCD gene. The UCD gene encodes for a protein that acts as an allosteric activator of the protein p101. The p101 protein is a histone acetyl transferase (HAT) which is an enzyme that acetylates histones when the protein is in its active form A different lung cancer cell line is found to have significantly decreased amounts of histone acetylation. Which...
In eukaryotes, miR-5 is a microRNA with sequence complementarity to the 3 UTR of the mRNA transcript encoded by the UCD gene. The UCD gene encodes for a protein that acts as an allosteric activator of the protein p101. The p101 protein is a histone acetyl transferase (HAT) which is an enzyme that acetylates histones when the protein is in its active form In a lung cancer cell line, the p101 protein is overly active leading to misregulation of gene...
Which of the following statements regarding the TATA binding protein (TBP) are true: Recognizes a sequence that is similar are identical to 5'TATAAA3' Ο Ο Ο All are correct. It is considered a universal transcription factor It is a part of TEIID protein complex It binds to a consensus sequence The backbone of a DNA molecule is made up of phosphate groups made up of sugars made up of alternating phosphate and sugar groups Made up of alternating sugars and...
BONUS (10 points, 2 points each): Given below is a sequence of mRNA that is transcribed from a structural and mRNA: AUG CGC GOA UCC CCC ACC AGA ACG GAX UGA-3 G-C 1. Using the codon chart provided below, write down the predicted amino acid sequence of the protein the produced from this mRNA 3-UAC GCG EXU AGG GGG UGG UCU UGC COU 2). Write down the DNA sequence of the structural pene from which this mRNA sequence is transcribed...
5. ZBP1 binds mRNAs. How would you determine whether there is a specific sequence in the mRNA that is required for ZBP1 binding? (Hint: they discuss relevant techniques at the bottom of page 1899 in the article, but make sure you use your own words in your answer). (5 points)
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