Question

QUESTION 2 What qualitative effect would you expect each of the following to have on the Pso of hemoglobin? Explain. a. Increase in pH from 7.2 to 7.4 b. Increase in Pco, from 20 to 40 mm Hg c. Dissociation into monomer polypeptide chains d. Decrease in 2,3-BPG concentration from 7 mM to 5 mM in red cells.

Answer 1

Question 2 - what qualitatile effect would you expect each of the following to have. on the pso of hemoglobin ? a) Increase in pH from 7.2 to 7.4 Ans? As Increase in PH from 7.2 to 7: 4 h decrease in P50 occur As This increase in pill increases hemoglobin's affinity for oxygen through the Bohr effect, causing hemoglobin to pick up oxygen en your blood from your lungs iso it can transport it to your tissues. b) Increase in Pco, from 20 to 40 mm Hg. Ansa As Increase in Pco, from 20 to somm Hg causing O increwing in Pso hemoglobin. Even then carbon dioxide reacts with water to form carbonic acid, an increase in cor resuts in a decree decrease in blood pH, result in hemoglobin proteins rest-releasing their load of oxygen. Dissociation into monomer polypeptide cham Ans Heamoglobin is composed of four subunits If pisso ciation happen into monomer polypeptide chain happen then will decrease in pso 'hemoglobin.

each molecule of Hemoglobin is capable of carring four oxygen molecules. In order to transport oxygen efficiently Corporation between the four subunits in a haemoglobin molecule becomes mandatory.. d) Decrease in 2,3 BPG Concentration from 7mM to 5 mM in red cells. Ang?? Decrease in 2,3 BPG (2.3 bis phospho glyceric acid) from 7 more to 5mm in red cells. Will decrease in P50 Hemoglobin. decrease .P.50 will increase. Hemoglobin's affinity for oxygen.