Why would the lack of ApoE and LDL receptor increase the total cholesterol in the blood?
Why would the lack of ApoE and LDL receptor increase the total cholesterol in the blood?
Homework Answers
ApoE or Apolipoprotein E is a protein that binds to several receptors, out of which LDL receptor is one which binds majorly. ApoE and LDL receptor interact and function together in transporting and catabolising cholestrol present in the blood. ApoE carries cholestrol from the blood stream to cells of liver, astrocytes etc. where they bind to the LDL receptor present on the surface of cells. The LDL receptors transfer the cholestrol into cells where it is utilised for various purposes.The lack of ApoE and LDL receptor would thus lead to hypercholestremia or increased levels of cholestrol in blood , which can in turn lead to several other diseases such as cardiovascular disease, parkinson's etc.
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Why would the lack of ApoE and LDL receptor increase the total
cholesterol in the blood?
b. Why would the Apoe-/- mouse (Apolipoprotein E knockout mice (Apoe−/−) that cannot make ApoE protein)...
b. Why would the Apoe-/- mouse (Apolipoprotein E knockout mice (Apoe−/−) that cannot make ApoE protein) have less HDL and more VLDL cholesterol?
why is a non-fasting blood sample a preferred method to obtain lab values to calculate total LDL...
why is a non-fasting blood sample a preferred method to obtain lab values to calculate total LDL cholesterol based on lab values of 1) total cholesterol mg/dL 2) HDL cholesterol mg/dL 3) total triglycerides mg/dL
The liver can absorb cholesterol from peripheral tissues via the blood. This process is known as...
The liver can absorb cholesterol from peripheral tissues via the blood. This process is known as reverse cholesterol transport. Which is considered to be the quantitatively most significant way in which liver hepatocytes take up cholesterol from human peripheral tissue? a. Cholesterol is amphipathic and circulates in the blood freely or bound to globulins, from which it is primarily taken up by the hepatocytes by direct incorporation into the plasma membrane. b. Cholesterol is primarily taken up by endocytosis of...
The liver can absorb cholesterol from peripheral tissues via the blood. This process is known as...
The liver can absorb cholesterol from peripheral tissues via the blood. This process is known as lapel cholesterol transport. Which is considered to be the quantitatively significant way in which liver hepatocytes absorb cholesterol from peripheral tissues in man? a. Cholesterol is primarily absorbed from HDL particles that are drained of cholesterol by binding to Scavenger Receptor B1 in the plasma membrane of hepatocytes. b. Cholesterol is absorbed primarily by lipoprotein lipase-catalyzed hydrolysis of colesterylestre in triglyceride- and colesterylester-rich VLDL...
A family member recently found out that he has high LDL cholesterol and low HDL cholesterol....
A family member recently found out that he has high LDL cholesterol and low HDL cholesterol. He has been advised by his doctor to change his diet to help improve these cholesterol levels and reduce the risk of heart disease. Describe 2 specific dietary changes he could make to his typical lunch to improve these blood cholesterol values. You may increase, decrease, add or replace current items in the diet. Then explain how these changes will improve his blood cholesterol...
2. All lipoproteins are made up of proteins, triglycerides, and cholesterol. Why are low-density lipoproteins (LDL)...
2. All lipoproteins are made up of proteins, triglycerides, and cholesterol. Why are low-density lipoproteins (LDL) considered unhealthy, and people encouraged to lower LDL, while high-density lipoproteins are considered healthy and people encouraged to increase HDL?
QUESTION 55 The numbers for good/bad cholesterol are: □ 1. Total Cholesterol <200, HDL>40, LDL< 130...
QUESTION 55 The numbers for good/bad cholesterol are: □ 1. Total Cholesterol <200, HDL>40, LDL< 130 0 2. Total Cholesterol <150, HDL>50, LDL<120 O 3 Total Cholesterol 150, HDL<50, LDL>120 4. Total Cholesterol 200, HDL<40, LDL 130 QUESTION 56 More men die by suicide, more women suicide QUESTION 57 are a leading cause of death not often reported QUESTION 58 Save All Answe .Naruto bubbed Vocabulary.com QUESTION 58 1.0 The following topics can be direct threats to the health and...
QUESTION 30 1 points Save Answer Heart disease is characterized by: a. low blood LDL cholesterol...
QUESTION 30 1 points Save Answer Heart disease is characterized by: a. low blood LDL cholesterol b. low blood pressure c. high blood HDL cholesterol d. high blood VLDL cholesterol e. low body fatness QUESTION 31 1 points Save Answer Which of the following types of chemical compounds can be used to lose body fluids? a. Antipyretics b. Analgesics c. Antibiotics d. Stimulants e. Diuretics
Why are LDL low density lipoproteins considered to be the "bad" cholesterol relative to the high...
Why are LDL low density lipoproteins considered to be the "bad" cholesterol relative to the high density lipoprotein particles? A) HDL particles contain a different form of cholesterol B) Because the lower the density of the particle, the more cholesterol it contains. C) Because HDL receptors are not found on cells
What is the best meal to help reduce LDL cholesterol levels in the blood? O roast...
What is the best meal to help reduce LDL cholesterol levels in the blood? O roast beef, mashed potatoes, tossed salad, sourdough bread Opinto beans and ham, corn on the cob with margarine, cornbread O grilled salmon, wild rice, steamed broccoli, and whole wheat roll O roasted chicken, sweet potatoes, green peas, and low-fat biscuit
The liver can absorb cholesterol from peripheral tissues via the blood. This process is known as lapel cholesterol transport. Which is considered to be the quantitatively significant way in which liver hepatocytes absorb cholesterol from peripheral tissues in man? a. Cholesterol is primarily absorbed from HDL particles that are drained of cholesterol by binding to Scavenger Receptor B1 in the plasma membrane of hepatocytes. b. Cholesterol is absorbed primarily by lipoprotein lipase-catalyzed hydrolysis of colesterylestre in triglyceride- and colesterylester-rich VLDL...
A family member recently found out that he has high LDL cholesterol and low HDL cholesterol. He has been advised by his doctor to change his diet to help improve these cholesterol levels and reduce the risk of heart disease. Describe 2 specific dietary changes he could make to his typical lunch to improve these blood cholesterol values. You may increase, decrease, add or replace current items in the diet. Then explain how these changes will improve his blood cholesterol...
2. All lipoproteins are made up of proteins, triglycerides, and cholesterol. Why are low-density lipoproteins (LDL) considered unhealthy, and people encouraged to lower LDL, while high-density lipoproteins are considered healthy and people encouraged to increase HDL?
QUESTION 55 The numbers for good/bad cholesterol are: □ 1. Total Cholesterol <200, HDL>40, LDL< 130 0 2. Total Cholesterol <150, HDL>50, LDL<120 O 3 Total Cholesterol 150, HDL<50, LDL>120 4. Total Cholesterol 200, HDL<40, LDL 130 QUESTION 56 More men die by suicide, more women suicide QUESTION 57 are a leading cause of death not often reported QUESTION 58 Save All Answe .Naruto bubbed Vocabulary.com QUESTION 58 1.0 The following topics can be direct threats to the health and...
QUESTION 30 1 points Save Answer Heart disease is characterized by: a. low blood LDL cholesterol b. low blood pressure c. high blood HDL cholesterol d. high blood VLDL cholesterol e. low body fatness QUESTION 31 1 points Save Answer Which of the following types of chemical compounds can be used to lose body fluids? a. Antipyretics b. Analgesics c. Antibiotics d. Stimulants e. Diuretics
What is the best meal to help reduce LDL cholesterol levels in the blood? O roast beef, mashed potatoes, tossed salad, sourdough bread Opinto beans and ham, corn on the cob with margarine, cornbread O grilled salmon, wild rice, steamed broccoli, and whole wheat roll O roasted chicken, sweet potatoes, green peas, and low-fat biscuit
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