Question

The liver can absorb cholesterol from peripheral tissues via the blood. This process is known as lapel cholesterol transport. Which is considered to be the quantitatively significant way in which liver hepatocytes absorb cholesterol from peripheral tissues in man? a. Cholesterol is primarily absorbed from HDL particles that are drained of cholesterol by binding to Scavenger Receptor B1 in the plasma membrane of hepatocytes. b. Cholesterol is absorbed primarily by lipoprotein lipase-catalyzed hydrolysis of colesterylestre in triglyceride- and colesterylester-rich VLDL particles and chylomicrowns. c. The cholesterol is amfifatic and circulates in the blood freely or bound to globulins, from which it is primarily absorbed by the hepatocytes by direct incorporation into the plasma membrane. d. Cholesterol is absorbed primarily by endocytosis of colesterylester-rich LDL particles and chylomicronresidues (chylomicron remnants)via the LDL receptor and LDL receptor-related protein. e. The cholesterol is amfifatic and circulates in the blood, freely or bound to globulins, from which it is primarily absorbed by hepatocytes by aid of transport proteins in the plasma membrane.

Answer 1

Anower: - a cholestrol in primarily abombed from HOL particles That are drained of cholestrole by binding to Scavenger Reupton B1 in the plovne membrane of hepatocytes Noteri- some information about HOL porticle to & outs membrane Colestrol exter in amphipathi rich in hydrophobic core 9 1402 particle enzyme such as also helpful in carry decithin colestrol, LCAT Coleohole transport drep :- Ipheripheral fioue - Blood - I liver Here "LCAS" enzyme are helpful in converting of :- Colewhole colestole ester LCAT 0 HD2 HD23 y convert PL YA Pin in to fet LAN) ft Lcar Teng HOLZ Completely form and hind with SR B2 [NO2 Recepten) and giver Colestrol epten