Question

In eukaryotic genomes, regions of _____________________ are transcriptionally active while regions of ____________________ are transcriptionally silent.

A) Heterochromatin; euchromatin

B) Euchromatin; heterochromatin

C) None of the above

Which of the following proteins can regulate eukaryotic gene expression WITHOUT binding to the DNA in the regulatory region?

A) repressors

B) enhancers

C) co-activators

D) transcription factors

In eukaryotes, transcriptional activity can be regulated by methylation of a dinucleotide sequence called "CpG." This modification occurs at a:

A) Adenine

B) Cytosine

C) Guanine

D) Thymine

In a single cell type, Gene A requires the binding of TF1, TF2 and TF3 to its regulatory region, while Gene B requires the binding of TF1, TF3 and TF4 to its regulatory region. How would a mutation in the gene for TF2 affect the expression of these two genes?

A) Both genes would be expressed

B) Gene A would be expressed, but Gene B would not

C) Gene B would be expressed, but Gene A would not

D) Neither gene would be expressed

For eukaryotic genes, alternative mRNAs produced from the same gene are called:

A) Isoforms

B) Isomers

C) Isotopes

D) None of the above

Answer 1

1.In Eukaryotic genomes regions of Euchromatin is transcriptionally active while regions of Heterochromatin are transcriptionally silent.Euchromatin is loosely packed regions of chromatin.These are lightly_stained region.Heterochromatin is densely packed regions of chromatin and darkly stained regions.

2.Enhancer protein can make Gene expression without binding regulatory Gene.

3.In capping ,an unusual nucleotide ,methyl guanosine triphosphate (​​​​​m​​​​​G​​​​​ppp ) is added to the 5'end of hnRNA.That is the methylation occur at Guanine.

4. Gene B would be expressed but Gene A would not. TF II D protein is essential for tanscription of gene.

5.For Eukaryotic genes, alternate mRNAs is produced from same Gene are called isoforms.

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