Homework Answers
The answer is D (both A and B are true).
A.Suppressor mutation may result in a second site reversion of a mutation by reverting a point mutation or mutation due to addition of a gene sequence. This brings back the wild type genotype from the initial mutated one.
B. Suppressor mutation can correct a nonsense mutation as in case of tRNA mediated suppression. A mutation in tDNA (DNA coding for tRNA) gene results in coding for a stop codon instead of a sense codon, which further results in formation of incomplete polypeptide chain. Suppressor mutation causes insertion of relative amino acid (Tyr, Gln or Lys for UAG and UAA stop codons, while Cys, Trp and Arg for UGA stop codon) instead of stopping the translation process and thus produces a normal polypeptide chain.
And since the suppressor mutation occurs in the gene of a tDNA, and not the tRNA, the C option is incorrect.
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