Homework Answers
Q21)
Silent mutation.
If TGT (UGU) were mutated to TGC (UGC), the amino acid added in the protein would not change, as both UGU and UGC code for Cysteine. Therefore, this is a silent mutation.
Q22)
Nonsense mutation.
If TGT (UGU) were mutated to TGA (UGA), then this would be a Nonsense mutation. Nonsense mutations are mutations where a premature stop codon prevents the formation of the complete protein. Here, the mutated codon, UGA, is a stop codon, and therefore, the mutation is a nonsense mutation.
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19 Duco Puco Puco poco Thin BeeCode SATGATA CAC CTA GGA ACT GTC AAC CCT TGT...
A close up of a receipt Description automatically generated 5'ATGATA CACCIA GGA ACT GTC AAC CCI...
A close up of a receipt Description automatically generated 5'ATGATA CACCIA GGA ACT GTC AAC CCI IGT* TGI CACIGA AGA 3' If the base highlighted in bold and marked with an * were mutated to a guanine, what sort of mutation would this be? Silent mutation Missense mutation Nonsense mutation Deletion Insertion A close up of a receipt Description automatically generated 5'ATGATA CAC CTA GGA ACT GTCAAC CCTTGT* TGT CAC TGA AGA 3 If the base highlighted in bold and...
The following sequence represents triplets on DNA TAC CAG ATA CAC TCC CCT GCG ACT A....
The following sequence represents triplets on DNA TAC CAG ATA CAC TCC CCT GCG ACT A. Give the mRNA codons and tRNA anticodons that correspond with this sequence. B. Using the above piece of DNA, show a deletion, insertion, a substitution, and nonsense mutation. Which ones are frame-shift mutations? Are any of your mutations missense? Use the table of codons and amino acids in the textbook to answer this part of the question. For microbiology
can i get help with this question please Reference Sequence Wild-Type DNA Template Sequence: mRNA Sequence:...
can i get help with this question please
Reference Sequence Wild-Type DNA Template Sequence: mRNA Sequence: Amino Acid Sequence: TAC ACC TTG GCG ACG ACT AUG UGG AAC CGC UGC UGA Met-Top-Asn--Ars--Y-STOP NS. Mutated DNA Template Sequence #5: TAC ACC TTG GGA CGA CT Compare the mutated DNA#5 with the wild-type DNA sequence. Do you observe a substitution, deletion, or insertion mutation? The mRNA sequence derived from mutated DNA #5 is AUG UGG AAC CCU GCU GA Use Table 10.3...
The following sequence represents triplets on DNA: TAC CAG ATA CAC TCC CCT GCG ACT a....
The following sequence represents triplets on DNA: TAC CAG ATA CAC TCC CCT GCG ACT a. Give the mRNA codons and tRNA anticodons th b. c. Induce an insertion of one nucleotide in the original sequence? Do the same for 2 nucleotides then 3 d. Substitute one nucleotide in the original sequence. How does each insertion affect the amino acid at correspond with this sequence, and then give the sequence of amino acids in the polypeptide. induce a deletion in...
mRNA transcr leaves the mucl ke protcins Th eings the amino no acids anre the bui...
mRNA transcr leaves the mucl ke protcins Th eings the amino no acids anre the bui ead in onder to. start and stop mak Land when to stot C. Use your codon chart to determine the amino acid sequence. Remember to read through the strand and ONLY start on AUG and STOP when it tells you to stop Follow example below Example: DNA AGA CGG TAC CTC CGG TGG GTG CTT GTC TGT ATC CTT CTC AGT ATC UCU GCC...
Describe what kind of mutation this allele has (e.g. insertion, deletion, substitution), which codon it is...
Describe what kind of mutation this allele has (e.g. insertion, deletion, substitution), which codon it is in, what effect it will have on the protein (e.g. nonsense missense, silent) as well as the amino acid change it will cause if it is a substitution. Refer to the genetic code. U UUU C UCU Uục Phe UCC Ser UUA UUG CUU UCA UCG CCU CCC Α UAU UAC y UGC cys UAA Stop UGA Stop UAG Stop UGG trp CGU CAC"...
Adenosine deaminases modify adenosines to form _____________________, which is then read as _________________________ by the translation...
Adenosine deaminases modify adenosines to form
_____________________, which is then read as
_________________________ by the translation and splicing systems,
as well as by reverse transcriptase.
Cephalopods like squid and octopus use this form of editing very
extensively in their protein-coding regions. For each of
the following, please indicate how these enzymes can alter the mRNA
to produce the indicated codon changes.
I (Ileu) is changed to V (val):
K (Lys) is changed to E (Glu):
T (Thr) is changed to A (ala):...
D) Consider that during replication of the cell. the following mutations were generated within the gene...
D) Consider that during replication of the cell. the following mutations were generated within the gene sequence. Find the mutation (in bold Italics-underlined Specify the protein sequences for each mutant sequence. mutation type 1: This is a non-sense mutation because the codon does not code for an amino acid any more 5' -..AACTAATGCCGTAAGACGTATTTTGACTAAT..-3' (substitution of a C 7 A in codon 3) 3'- TTGATTACGGCAT ICTGCATAAAACTGATTA..-5 S mutation type 2: This is a missense mutation because the codon now codes for...
A single mutation has occurred in the following DNA sequence. 5' ATG AAA TTA CCA 3'...
A single mutation has occurred in the following DNA sequence. 5' ATG AAA TTA CCA 3' wild-type (normal) sequence 5' ATG AAG TTA CCA 3' mutant sequence (a) Identify and classify the mutation according to its molecular structure (i.e., insertion, deletion base substitution (transversion), or base substitution (transition)). Briefly explain why you selected this classification (1.75 marks) (b) Identify and classify the mutation according to its functional effects (i.e., frameshift, missense, nonsense, or silent). Briefly explain why you selected this...
A close up of a receipt Description automatically generated 5'ATGATA CACCIA GGA ACT GTC AAC CCI IGT* TGI CACIGA AGA 3' If the base highlighted in bold and marked with an * were mutated to a guanine, what sort of mutation would this be? Silent mutation Missense mutation Nonsense mutation Deletion Insertion A close up of a receipt Description automatically generated 5'ATGATA CAC CTA GGA ACT GTCAAC CCTTGT* TGT CAC TGA AGA 3 If the base highlighted in bold and...
can i get help with this question please
Reference Sequence Wild-Type DNA Template Sequence: mRNA Sequence: Amino Acid Sequence: TAC ACC TTG GCG ACG ACT AUG UGG AAC CGC UGC UGA Met-Top-Asn--Ars--Y-STOP NS. Mutated DNA Template Sequence #5: TAC ACC TTG GGA CGA CT Compare the mutated DNA#5 with the wild-type DNA sequence. Do you observe a substitution, deletion, or insertion mutation? The mRNA sequence derived from mutated DNA #5 is AUG UGG AAC CCU GCU GA Use Table 10.3...
The following sequence represents triplets on DNA: TAC CAG ATA CAC TCC CCT GCG ACT a. Give the mRNA codons and tRNA anticodons th b. c. Induce an insertion of one nucleotide in the original sequence? Do the same for 2 nucleotides then 3 d. Substitute one nucleotide in the original sequence. How does each insertion affect the amino acid at correspond with this sequence, and then give the sequence of amino acids in the polypeptide. induce a deletion in...
mRNA transcr leaves the mucl ke protcins Th eings the amino no acids anre the bui ead in onder to. start and stop mak Land when to stot C. Use your codon chart to determine the amino acid sequence. Remember to read through the strand and ONLY start on AUG and STOP when it tells you to stop Follow example below Example: DNA AGA CGG TAC CTC CGG TGG GTG CTT GTC TGT ATC CTT CTC AGT ATC UCU GCC...
Describe what kind of mutation this allele has (e.g. insertion, deletion, substitution), which codon it is in, what effect it will have on the protein (e.g. nonsense missense, silent) as well as the amino acid change it will cause if it is a substitution. Refer to the genetic code. U UUU C UCU Uục Phe UCC Ser UUA UUG CUU UCA UCG CCU CCC Α UAU UAC y UGC cys UAA Stop UGA Stop UAG Stop UGG trp CGU CAC"...
Adenosine deaminases modify adenosines to form
_____________________, which is then read as
_________________________ by the translation and splicing systems,
as well as by reverse transcriptase.
Cephalopods like squid and octopus use this form of editing very
extensively in their protein-coding regions. For each of
the following, please indicate how these enzymes can alter the mRNA
to produce the indicated codon changes.
I (Ileu) is changed to V (val):
K (Lys) is changed to E (Glu):
T (Thr) is changed to A (ala):...
D) Consider that during replication of the cell. the following mutations were generated within the gene sequence. Find the mutation (in bold Italics-underlined Specify the protein sequences for each mutant sequence. mutation type 1: This is a non-sense mutation because the codon does not code for an amino acid any more 5' -..AACTAATGCCGTAAGACGTATTTTGACTAAT..-3' (substitution of a C 7 A in codon 3) 3'- TTGATTACGGCAT ICTGCATAAAACTGATTA..-5 S mutation type 2: This is a missense mutation because the codon now codes for...
A single mutation has occurred in the following DNA sequence. 5' ATG AAA TTA CCA 3' wild-type (normal) sequence 5' ATG AAG TTA CCA 3' mutant sequence (a) Identify and classify the mutation according to its molecular structure (i.e., insertion, deletion base substitution (transversion), or base substitution (transition)). Briefly explain why you selected this classification (1.75 marks) (b) Identify and classify the mutation according to its functional effects (i.e., frameshift, missense, nonsense, or silent). Briefly explain why you selected this...
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