Question

Insert numbers from the answer list below into the sentence's blanks to correct the statement. Enzyme is important for lipolysis during fasting. Enzyme activity of insulin. (1) acetyl-CoA carboxylase (2) acyl-CoA synthetase (3) adrenalin (4) carnitin palmitoyltransferasel (5) cholesteryl ester transfer protein (6) Fatty acid synthase (7) glucagon (8) HMG-CoA lyase (9) HMG-CoA reductase (10) hormonsensitiv lipase (11) insulin (12) lecithin-cholesterol acyltransferase (13) lipoprotein lipase (14) thiolase (15) inhibited/reduced (16) stimulated/increased

Answer 1

Along with explaining about the answers I have also given an overview about the requirement of lipolysis during fasting and the results of it so that you can understand it in better way...

@ Enzyme hormone -Arnsitive lipase is important for Lipolysis during fasting. Enzyme activity is inhibited / reduced of insulin. Ans: Before going for explanation I want to clear that although glucagon, adrenalin etc. are associated with the lipolysis process, but these are hormones. So I have an selected these from answer. in human being the extra amount of nutrient on hood which one take care generally stored as pats in their body. So when one do farting, they are devoid of getting energy from food, from which they regularly get energy, but the body requires energy for & le normal functioning. Hence in Auch case the previr ously stored fat are hydrolyzer / Catalyses to free fatty acido (AFA) molecules from which the individe- al'a body make cep the breagy requirements this process of generation of FFA from stored fat is known as lipolysis Generally the enzyme hormone sensitive lipase is responsible for lipolysis. Crenerally hormone sensitive lipase (HSC) results a Gatty acid & diglyceride molecule from triacylglycenol molecule or catalyzes a diglycerol molecule into a hatty acid or & monoglyceride.

HSL is also called as triglyceride, while the enzyme cleaving and fatty acid from triglyceride is known as diglyceride lipase & the third enzyme cleaving the final fatty acid from d'acrylglyceride is lenocom as mono a cyl glyceride lipase. out of which these 3 enzymes only the first enzyme is affected by hormone & hence called as hormone sensitive lipase CHSL) & is considered as the most prominent enzyme taking part in the process of lipolysis. Also in rat it is shown that the level of Hst increases along with the increasing level of FFA & hence is considered as the enzyme responsible for lipolysis during lasting. Also, as we have discussed earlier, that the HSL is activated by the hormones like catecholamines & adrenaline. Initially it was thought that anong the pancreatic hormones, glucagon has more act wating effect on HSL, but when the path of insulin was out off, the activation of HSL was seen effectively & the inhibit anory effect of insulin was recognised. In general it was found that glucagon has less effect on the lipolytic activity in humans adipose tissue (where hat are get stored). per