What mechanism based on the metabolic intermingling of folate and choline metabolism to help with attenuating fatty liver or liver dysfunction?
Choline is an essential nutrient and the liver is a central organ which responsible for choline metabolism.Humans eating low-choline diets develop fatty liver and liver damage. This dietary requirement for choline is modulated by estrogen and by single-nucleotide polymorphisms in specific genes of choline and folate metabolism. The spectrum of choline's effects on liver range from steatosis to development of hepatocarcinomas, and several mechanisms for these effects have been identified. They include abnormal phospholipid synthesis, defects in lipoprotein secretion, oxidative damage caused by mitochondrial dysfunction, and endoplasmic reticulum stress. Furthermore, the hepatic steatosis phenotype can be characterized more fully via metabolomic signatures and is influenced by the gut microbiome. Importantly, the intricate connection between liver function, one-carbon metabolism, and energy metabolism is just beginning to be elucidated.
What mechanism based on the metabolic intermingling of folate and choline metabolism to help with attenuating...
How might choline deficiency be contributing to the fatty liver and liver dysfunction? Propose two mechanisms based on the physiological functions of this nutrient.
Which of the following statements best describes the difference between aerobic and anaerobic metabolism? Check all that apply. - Anaerobic metabolism produces more ATP than aerobic metabolism. - Anaerobic metabolism produces less ATP than aerobic metabolism. - Only aerobic metabolism can occur in the absence of oxygen. - Anaerobic metabolism does not produce lactate while aerobic metabolism does. - Both anaerobic and aerobic metabolism run through glycolysis, Krebs cycle, and the electron transport chain. - Only anaerobic metabolism can occur...
Based on these metabolic pathways, what is there source of electrons for obtaining NADPH? What are the donors and acceptors in the electron transport chain? 溜貍 A. co CO c0, Amino ades Amino acks Faity adds ET.C s-s of bacterial metabolism. The pathways are simplified: only key compounds are shown. ClM, cell membrane on transport chain; PS, photosystem. Notice that the reactions are not stoichiometrically balanced
Which of the following metabolic changes will occur in a typical human after a meal balanced in carbohydrates, protein, and fat is consumed? (Select ALL that apply!) Liver glycogen synthesis increases Muscle glycogenolysis (glycogen breakdown) increases Liver gluconeogenesis decreases Insulin levels in the blood decrease Ketone body production in the liver is increased ..... Which of the following metabolic changes will occur in a typical human during 12 hours of fasting? (Select ALL that apply.) Liver glycogen synthesis decreases Liver...
Please help with the following 2 questions: 1) What are different examples of metabolic profiling? How are each used to understand different patterns of data? 2) How does Glycolysis contribute to energy metabolism? Describe the process of Glycolysis with words.
What enzymatic mechanism(s) contributes to glycogen metabolism? Please explain fully
Based on your knowledge of cell signaling and interorgan metabolism, describe how the fuel metabolism of the liver, adipose tissue, skeletal muscle, heart and brain are affected in type I diabetics (assuming no insulin shot has been used) immediately after a meal and between meals. Include what pathways have been affected (glycolysis, glycogen synthesis, etc) and what the organ/tissue uses as a fuel source.
QUESTION: you run away from fear of a large snake. Explain: what happens to your metabolism during your run. explain how metabolism changes over time. Please discuss what fuels are providing the energy at each point in time and how organs differ in their fuel usage. be sure to discuss what happens to carbohydrate and lipid metabolism in your major organs (brain, muscle, liver, fat cells, and heart) under each circumstance. Also explain briefly HOW each organ shifts its fuel usage...
1. Reversible phosphorylation is a control mechanism usedthroughout metabolism. What are the general names of the enzymes involved in reversible phosphorylation and what general reactions do they catalyze?
Reversible phosphorylation is a control mechanism used throughout metabolism. What are the general names of the enzymes involved in reversible phosphorylation and what general reactions do they catalyze?