The human blood cell is an enucleated (no nucleus) and flattened cell that lacks intracellular organelles but provides essential functions such as oxygen transport. In this cell, the ratio for proteins mass to phospholipids is 2: Assuming that the mass of the average membrane protein is 50 kilodalton compared to phospholipids (mass= 1000 daltons), approx. how many lipid molecules (i.e. phospholipids + cholesterol) are present for each protein molecule?
The answer key says: 100. Please explain and show work.
The mass of the average membrane
protein = 50 kDa
The mass of the average membrane phospholipid = 1000 Da = 1 kDa
The ratio of proteins mass to
phospholipids = 2
i.e. the protein mass is twice the lipid mass
However, the average protein molecular weight is 50 times greater
than the average molecular weight of a lipid.
So, the ratio between the number of protein molecules to lipid molecules = 1:100
Explanation:
Let us assume (Since the ratio between proteins to lipid is
2)
2 protein molecules = 20 X 50 = 100 kDa
For how many lipid molecules
represent 100 kDa
= 1 X 100
= 100 molecules
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