Question

*Microbiology. Please answer the below two multiple choice questions. The current selected answers are incorrect. Thank you, will provide positive feedback for correct answers!

Incorrect Question 3 0/1 pts The replication fork has both leading (continuous) and lagging (discontinuous) synthesis because: a. The origin of replication only allows DNA synthesis to occur in one direction around the chromosome. b. Primase only works on the leading strand c. Helicase is slow in unwinding the double helix so the polymerization moving toward the replication fork has to stop and start. d. The antiparallel arrangement of the complementary strands requires that DNA polymerase start at the replication fork and move away from it as it synthesizes the lagging strand

Answer 1

d is correct bcz DNA fragments are antiparallel .DNA polymerase work continously on leading strand .

& The replication fork has lagging synthesis because: both leading and (d) is correct. DNA segments are autiparallel . DNA polymerase work continously on leading strand. 131-3) Lagging strand replicate in opposite direction so it happens in small fragments (Okazaki fragments ) later joun by DNA ligase. (5'-3') 9- Ans: 5' to 3' polymerization means that (d) is correct. DNA polymerase add nucleotide in 5 to 3' direction. (leading strand). 5' end bears phosphate group and 3' end bear a hydroxyl group. It occurs in this direction b'coz DNA polymerase requires free 3' OH group to attach new nucleotide.