In the NFκB signaling pathway, which of the following molecules is downstream of IκB kinase? Select...
In the NFκB signaling pathway, which of the following molecules is downstream of IκB kinase? Select any/all answers that apply.
| A. |
NFκB |
|
| B. |
TNFα |
|
| C. |
TAK1 |
|
| D. |
IL-1 |
|
| E. |
Hedgehog |
Homework Answers
Answer: In NFkB signaling pathway, molecules downstream of IkB kinase are B.TNFalpha, C.TAK1, D. IL-1.
In resting cells, NFkB associated with IkB protein. IkB blocks the transcription of NFkB.
proinflammatory cytokines such as interleukin 1 (IL-1) and tumor necrosis factor α (TNFα) are associated with activation of NFkB signaling pathay.
TAK1 activates NFkB pathway by phosphorylating and activating of IKKs complex.
Add Answer to:
In the NFκB signaling pathway, which of the following molecules
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Which of the following is cleaved by regulated intramembrane proteolysis (RIP)? Select any/all answers that apply....
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1) The following cartoon illustrates a prototypical receptor tyrosine kinase cascade. Based on your knowledge of...
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answer the following questions that focus on the Ras GTPase enzyme
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help with 38 I got it wrong and dont know what it is what is ras?...
help with 38 I got it wrong and dont know what it
is
what is ras? is what is missing sorry
lilleonine kinase receptors D) Nuclear receptors E) Tyrosine phosphatase receptors D 37. Which one (if any) of the following cellular events does NOT inci wing cellular events does NOT include a role for apoptosis: A) Immune function return to homeostasis following an infection B) Digit formation during development C Cellular response to irreparable DNA damage identified in G1 of...
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Explain why.
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a) Complete the signal transduction cascade by filling in the empty
boxes with the identities of the molecules.
b) There's few mechanisms that lead to amplification of signal
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how it leads to signal amplification.
c) Indicate...
32. Study the signaling pathway illustrated below, which involves two different receptors. Assume that a protein is active only when it is activated, but not inhibited, by its upstream signaling molecules. Activation and inhibition are indicated by normal and blunt arrows, respectively. Assume that the transcription regulator can be activated by either the binding protein or the kinase that are immediately upstream of the transcription factor. Under which of the following conditions will the expression of target:gene "X" be induced?...
help with 38 I got it wrong and dont know what it
is
what is ras? is what is missing sorry
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