In the NFκB signaling pathway, which of the following molecules is downstream of IκB kinase? Select...
In the NFκB signaling pathway, which of the following molecules is downstream of IκB kinase? Select any/all answers that apply.
| A. |
NFκB |
|
| B. |
TNFα |
|
| C. |
TAK1 |
|
| D. |
IL-1 |
|
| E. |
Hedgehog |
Homework Answers
Answer: In NFkB signaling pathway, molecules downstream of IkB kinase are B.TNFalpha, C.TAK1, D. IL-1.
In resting cells, NFkB associated with IkB protein. IkB blocks the transcription of NFkB.
proinflammatory cytokines such as interleukin 1 (IL-1) and tumor necrosis factor α (TNFα) are associated with activation of NFkB signaling pathay.
TAK1 activates NFkB pathway by phosphorylating and activating of IKKs complex.
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In the NFκB signaling pathway, which of the following molecules
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help with 38 I got it wrong and dont know what it
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Explain why.
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a) Complete the signal transduction cascade by filling in the empty
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downstream of RTK pathway. Name one of those mechanisms and explain
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c) Indicate...
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help with 38 I got it wrong and dont know what it
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