Answer: The protein made by endoplasmic reticulum is first processed by Golgi apparatus before sending them out. Proteins enters Golgi with their cis side i.e facing the endoplasmic reticulum. Golgi stack traverses, as a new cis-golgi cisternae is formed, changing as it matures by accumulating medial, then comes the trans-golgi cisterna, that moves from later to earlier cisternae. And finally exit on the opposite side of the stack with their trans side i.e facing the plasma membrane of the cell.
Now, filling the blanks
a. Endoplasmic reticulum
b. cis-golgi cisternae
c. medial-golgi cisternae
d. trans-golgi cisterna
e. Plasma membrane
Proteins that are produced in rough ER to be secreted to the outside must first enter...
4. Ex plain how proteins produced in the rough endoplasmic reticulum can be secreted into the extracellular environment without ever crossing the plasma membrane. Use the terms rough endoplasmic reticulum ribosome, lumen, Golgi apparatus, cell membrane in your answer.
QUESTION 6 2 pc Many eukaryotic cells make proteins that ultimately are supposed to be secreted towards the outside of the cell. Place the following cell components in the order that they would function in the synthesis and export of one of these proteins. Note that Vesicle #1 must be used before Vesicle #2. G. Plasma membrane Vesicle #2 ANSWER is WRONG Golgi apparatus - trans face Ribosome A. Rough endoplasmic reticulum Vesicle #1 D. Golgi apparatus - cis face
Order the following statements to correctly describe the route of secreted protein as it is synthesized and secreted from a eukaryotic cell. A. The protein folds and undergoes modification within the rough ER. B. The protein travels within a membranous vesicle from the ER to the cis face of the Golgi apparatus. C. Translation begins on a ribosome. D. The protein travels toward the trans face of the Golgi, from which it is packaged into a secretory vesicle. E. The...
please answer all that you can 1. You have genetically engineered green fluorescent protein (GFP) containing a KDEL sequence (GFP-KDEL). When GFP-KDEL is expressed in normal human fibroblasts and examined using fluorescence microscopy, the fluorescence appears diffuse across the cytoplasm. How would you explain this observations given that KDEL is supposed to be an ER-specific sorting sequence? A. This engineered GFP would not have a hydrophobic signal sequence to get it into the RER in the first place. B. The...