Homework Answers
19. D
Both the traits are occurring only in 1st and 3rd Generation. It means they are skipping generations. This is a characteristic of recessive traits.
Both the traits are present only in males. When either males or females are affected, then the trait is said to be sex linked.
20. B
The most important feature of sex linked recessive trait is that that if a female is heterozygote for that trait, than 50% of the sons will be affected. From the Pedigree, we can see that some of the sons of II-1 are affected whereas one is unaffected
21. B
This is because of independent assortment of genes which occur during meiosis. This law states that alleles of one gene about independently of the alleles of other gene during gamete formation.
According to law of segregation, alleles of one gene separate in independently of each other.
22. D
Mapping distance = number of recombinants/ total number of progenies × 100
Considering only 1st and 3rd generations,
Parents = 1st generation
Progenies = parental (III-1 and III-4) and recombinants (III-2 and III-3)
Mapping distance = 2/4 × 100 = 50%
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(Q19-22) The pedigree on left shows the inheritance patterns of two diseases among human populations: one...
Please answer #19-22, explain and clearly indicate which # you are answering. Thank you so much!...
Please answer #19-22, explain and clearly indicate
which # you are answering. Thank you so much!
(Q19-22) The pedigree below shows the inheritance patterns of two diseases among human populations: one is indicated by a vertical line and the other indicated by a horizontal line. # 0 3 2 19. Which is the correct description of the two diseases? A. dominant and autosomal linked B. dominant and X-chromosomal linked C. recessive and autosomal linked D. recessive and X-chromosomal linked E....
(Q23-24) The pedigree on left shows the inheritance pattern of one human disease. • O HO...
(Q23-24) The pedigree on left shows the inheritance pattern of one human disease. • O HO 23. Which is the correct description of this disease? A. dominant and autosomal-linked B. dominant and X-chromosomal linked C. recessive and autosomal-linked D. recessive and X-chromosomal linked E. codominant and X chromosomal linked 3 24. What is the probability of an affected child from the marriage between 1 and 2? A. 0% B. 25% C. 50% D. 75% E. 100%
The pedigree below shows the inheritance pattern of a sex-linked allele for one family. What is...
The pedigree below shows the inheritance pattern of a sex-linked allele for one family. What is true about the genotype of individuall-2? 1-1 1-2 II-1 II-2 II-3 II-4 III-1 III-2 The disease is caused by a dominant allele (D) and his genotype is dd He must have the genotype X'Y The disease is caused by having two recessive alleles (dd) and his genotype is He has the recessive disease allele on his X chromosome XY He has the dominant disease...
please provide an explanation for both questions! Thank You! 9. Consider the pedigree to the right,...
please provide an explanation for both questions! Thank
You!
9. Consider the pedigree to the right, displaying the inheritance of a rare recessive autosomal disease which is fully penetrant. What is the likelihood that the child will be affected? a. 1/2 b. 27/81 c. 1/4 d. 1/36 e. 1/64 10. Consider the following pedigree from a human family containing a male with Klinefelter syndrome (a set of abnormalities seen in XXY individuals; indicated with a shaded box). In each, A...
Question 3 The following human pedigree shows a family affected by a specific disease. Assume that...
Question 3 The following human pedigree shows a family affected by a specific disease. Assume that the individuals marked with an asterisk () do not carry any allele associated with the affected phenotype and that no other mutation spontaneously occurs. Also assume complete penetrance a) State the most likely mode of inheritance for this disease. Choose from: autosomal dominant, autosomal recessive, X-linked dominant, X-linked recessive b) Write all possible genotypes of the following individuals in the pedigree. Use the uppercase...
What is the mode of inheritance for hypercholesterolemia? a. Autosomal dominant b. Autosomal recessive c. X-linked...
What is the mode of inheritance for hypercholesterolemia?
a.
Autosomal dominant
b.
Autosomal recessive
c.
X-linked dominant
d.
X-linked recessive
e.
More than one of the above are possible
----------------------------------------------------------------
What is the mode of inheritance for Hunter's syndrome?
a.
Autosomal dominant
b.
Autosomal recessive
c.
X-linked dominant
d.
X-linked recessive
e.
More than one of the above are possible.
------------------------------------------------------------
What is the genotype for individual II-3 at the
hypercholesterolemia locus (dominant allele is denoted by H,
recessive allele...
22. In the pedigree shown below it has been found that the disease (indicated by the...
22. In the pedigree shown below it has been found that the disease (indicated by the filled circles) is caused by a RARE autosomal recessive mutation in a gene that is paternally imprinted. What are the genotype(s) for individuals 1-2 and II-4, respectively? Imprinted alleles are identified with an asterisk. 1 II 6 성 모 . III 5 A) aa* and AA* B) aA* and Aa* C) aa* and Aa* D) Aa* and AA* E) aA* and AA*
The pedigree shows the occurrence of a X linked recessive mendelian disease in a human family....
The pedigree shows the occurrence of a X linked recessive mendelian disease in a human family. Two unaffected family members were genotyped at a microsatellite locus and two different microsatellite alleles were observed (M1 and M2) I M1/M1 II 1 M1 M2 III 3 IV 3 5 a) Assume the disease and the microsatellite locus are completely linked. What is the genotype of individual IV-4 (give both disease and micrsatellite alleles in the genotype)? b) Assume that the disease locus...
1) Two parents are affected by a disease but genetic testing shows that some of their...
1) Two parents are affected by a disease but genetic testing shows that some of their children don't have the disease allele at all. Which one of the reasons below could best explain this? A) The allele is X-linked and didn't affect their sons B) The allele causing the disease is co-dominant C) The allele causing the disease is autosomal dominant D) The allele causing the disease is autosomal recessive 2) Which one of these stages results in an increase...
In general, the following characteristics suggest (but do not prove) specific inheritance patterns: Autosomal recessive inheritance:...
In general, the following characteristics suggest (but do not prove) specific inheritance patterns: Autosomal recessive inheritance: -affected individuals can be born to unaffected parents -if both parents are affected, all children are affected -observable effect of relatedness (consanguinity) -horizontal" inheritance: trait appears at once among several members of one generation (siblings) *** Autosomal dominant inheritance each affected individual has an affected parent -when one parent is affected, transmission to the offspring (on average) *** -two unaffected parents do not transmit...
Please answer #19-22, explain and clearly indicate
which # you are answering. Thank you so much!
(Q19-22) The pedigree below shows the inheritance patterns of two diseases among human populations: one is indicated by a vertical line and the other indicated by a horizontal line. # 0 3 2 19. Which is the correct description of the two diseases? A. dominant and autosomal linked B. dominant and X-chromosomal linked C. recessive and autosomal linked D. recessive and X-chromosomal linked E....
(Q23-24) The pedigree on left shows the inheritance pattern of one human disease. • O HO 23. Which is the correct description of this disease? A. dominant and autosomal-linked B. dominant and X-chromosomal linked C. recessive and autosomal-linked D. recessive and X-chromosomal linked E. codominant and X chromosomal linked 3 24. What is the probability of an affected child from the marriage between 1 and 2? A. 0% B. 25% C. 50% D. 75% E. 100%
The pedigree below shows the inheritance pattern of a sex-linked allele for one family. What is true about the genotype of individuall-2? 1-1 1-2 II-1 II-2 II-3 II-4 III-1 III-2 The disease is caused by a dominant allele (D) and his genotype is dd He must have the genotype X'Y The disease is caused by having two recessive alleles (dd) and his genotype is He has the recessive disease allele on his X chromosome XY He has the dominant disease...
please provide an explanation for both questions! Thank
You!
9. Consider the pedigree to the right, displaying the inheritance of a rare recessive autosomal disease which is fully penetrant. What is the likelihood that the child will be affected? a. 1/2 b. 27/81 c. 1/4 d. 1/36 e. 1/64 10. Consider the following pedigree from a human family containing a male with Klinefelter syndrome (a set of abnormalities seen in XXY individuals; indicated with a shaded box). In each, A...
Question 3 The following human pedigree shows a family affected by a specific disease. Assume that the individuals marked with an asterisk () do not carry any allele associated with the affected phenotype and that no other mutation spontaneously occurs. Also assume complete penetrance a) State the most likely mode of inheritance for this disease. Choose from: autosomal dominant, autosomal recessive, X-linked dominant, X-linked recessive b) Write all possible genotypes of the following individuals in the pedigree. Use the uppercase...
What is the mode of inheritance for hypercholesterolemia?
a.
Autosomal dominant
b.
Autosomal recessive
c.
X-linked dominant
d.
X-linked recessive
e.
More than one of the above are possible
----------------------------------------------------------------
What is the mode of inheritance for Hunter's syndrome?
a.
Autosomal dominant
b.
Autosomal recessive
c.
X-linked dominant
d.
X-linked recessive
e.
More than one of the above are possible.
------------------------------------------------------------
What is the genotype for individual II-3 at the
hypercholesterolemia locus (dominant allele is denoted by H,
recessive allele...
22. In the pedigree shown below it has been found that the disease (indicated by the filled circles) is caused by a RARE autosomal recessive mutation in a gene that is paternally imprinted. What are the genotype(s) for individuals 1-2 and II-4, respectively? Imprinted alleles are identified with an asterisk. 1 II 6 성 모 . III 5 A) aa* and AA* B) aA* and Aa* C) aa* and Aa* D) Aa* and AA* E) aA* and AA*
The pedigree shows the occurrence of a X linked recessive mendelian disease in a human family. Two unaffected family members were genotyped at a microsatellite locus and two different microsatellite alleles were observed (M1 and M2) I M1/M1 II 1 M1 M2 III 3 IV 3 5 a) Assume the disease and the microsatellite locus are completely linked. What is the genotype of individual IV-4 (give both disease and micrsatellite alleles in the genotype)? b) Assume that the disease locus...
In general, the following characteristics suggest (but do not prove) specific inheritance patterns: Autosomal recessive inheritance: -affected individuals can be born to unaffected parents -if both parents are affected, all children are affected -observable effect of relatedness (consanguinity) -horizontal" inheritance: trait appears at once among several members of one generation (siblings) *** Autosomal dominant inheritance each affected individual has an affected parent -when one parent is affected, transmission to the offspring (on average) *** -two unaffected parents do not transmit...
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