Question

You wish to create a transgenic mouse that is completely hairless. You introduce the appropriate mutation into embryonic stem cells and implant those cells into early embryos. Those embryos are placed in a surrogate mouse who then gives birth to the first generation of mice. These mice are further bred.

Which of the following is(are) true?

A) First generation is completely hairless

B) Second generation is completely hairless

C) Third generation is completely hairless

D) Second generation is heterozygous

E) Second generation are crossed with each other

F) First generation are crossed with each other

Answer 1

The following statements are true:
A.) First generation is completely hairless
F.) First generation are crossed with each other.

The embryos are engineered genetically by introducing mutated ES cells and then these embryos are placed in surrogate mouse.The first generation will be completely hairless as they were born from the surrogate mouse with the genetically .engineered embryo.In order to carry this transgene from one generation to another,first generation are crossed with each other.