Which of the following is NOT a DNA repair mechanism?
a. base excision in which bulky lesions are removed and replaced with the original nucleotides
b. direct repair of a modified base to the original structure
c. repair of mismatched bases to the original pair of nucleotides on opposite strands
d. replacement of nucleotides without the use of the complementary strand as a template
e. all of the above
Ans) d is not a repair mechanism, it is referred to substitution which is a type of mutation that occurs on DNA which replaces nucleotide without the help of a comlementary strand. While the others namely option a refers to base excision repair wherein nucleotides are added by DNA polymerase after the removal of short stretch of damaged polynuceotides., option b refers to direct repair which are usually UV radiation mediated repair of nucleotides, option c refers to the mismatch repair which involves identificaton of mismatched pairs, determine the base which has been misatched and removal of the same followed by replacement of correct base pair.
Which of the following is NOT a DNA repair mechanism? a. base excision in which bulky...
Which of the examples listed is not a DNA repair mechanism? direct repair base‑excision repair nucleotide‑excision repair insertion sequence repair mismatch repair
Which of the following are the 3 steps involved in the basic mechanism of DNA repair? (3 answers expected) a.) The segment of damaged strand is excised. b.) A repair DNA polimerase fills in the missing nucleotides using the bottom strand as a template. c.) DNA ligase seals the nick. d.) DNA ligase excises the segment of damaged strand. e.) Topoisomerase fills in the missing nucleotides using the bottom strand as a template.
Photoreactivation is called a direct reversal of DNA damage. Mismatch repair, Nucleotide excision repair and base excision repair correct DNA mismatches and damaged bases, but these systems are not considered direct repair. what two general steps do these indirect repair systems have in common?.
Which are true about direct repair of DNA? O The damaged base is excised and a new segment of DNA is synthesized to fill in the gap. Error-prone DNA polymerases are used to insert a nucleotide opposite to the damaged base. O A damaged base is restored to its correct structure without removing it from the DNA. O DNA ligase is needed. O Methylation marks can be used to distinguish the correct strand from the incorrect strand.
There is only ONE correct answer. Attached at the bottom is an information "Help" sheet that may or may not contain useful information pertaining to this question. 19. The integrity of the genetic code relies on high-fidelity DNA replication, in which information in a template strand of DNA is transferred to the newly synthesized daughter strand (with A opposite T, and G opposite C). In class, we discussed the results of an experiment in which an unnatural thymine isostere called...
Which of the following statements about DNA replication is FALSE? Primase synthesizes the primers. DNA polymerase is required to add new nucleotides to the growing ends of the DNA strands. DNA ligase joins the small DNA fragments of the lagging strand. Only one strand of the parent DNA serves as a template for a newly synthesized complementary strand.
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DNA mismatch repair enzymes preferentially repair bases on the newly synthesized DNA strand, using the old DNA strand as the template. If mismatches were simply repaired without regard for which strand served as template, would this reduce replication errors? Explain your answer (5 pts) Describe DNA replication (remember to mention all the enzymes involved) (10 pts)
Each of the following statements about the structure of DNA may be either true or false. Choose the appropriate answer for each of these statements. Bonding between adenine and thymine on opposite strands involves two hydrogen bonds. Nitrogenous bases are located on the outside of the double helix: phosphates are located towards the middle of the double helix. Bonding between guanine and cytosine on opposite strands involves three hydrogen bonds. DNA and RNA are structurally different due to the difference...
A) Which property of DNA replication enables accurate mismatch repair to prevent mutation? a) Adenine methylase lags behind the DNA polymerase b) the proofreading ability of DNA polymerase c) the error-free nature of DNA pol. III d) the sister chromatid can be used as a template B) which DNA repair mechanism uses the sister chromatid as a template for repair? a) nucleotide excision repair b) double-stranded break repair c) postreplication repair d) base excision repair C) indicate which substitutions require...