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How do high temperatures, extremes in pH and high salt concentrations affect enzymes?

How do high temperatures, extremes in pH and high salt concentrations affect enzymes?
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At low temperatures, an increase in temperature increases the rate of an enzyme-catalyzed reaction. At higher temperatures the protein is denatured, and the rate of the reaction dramatically decreases. An enzyme has an optimum pH range in which it exhibits maximum activity.
-Increasing salt concentration means increasing the amount of ions in solution. These ions can disrupt the electrostatic interactions between amino acids that holds the tertiary structure together since correct protein folding is absolutely necessary for the function of the enzyme , this can render the enzyme nonfunctional , or denatured the enzyme .

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