Question

What happens when IGF-1 levels get too high?

Answer 1

ANSWER:

High level of IGF-1 can cause abnormal growth of the skeleton and other signs and symptoms characteristic of two rare conditions, gigantism and acromegaly.(rate if answer is helpful)

Acromegaly may produce the following signs and symptoms, which can vary from one person to another:

• Enlarged hands and feet.
• Coarsened, enlarged facial features.
• Coarse, oily, thickened skin.
• Excessive sweating and body odor.
• Small outgrowths of skin tissue (skin tags)
• Fatigue and muscle weakness.

Gigantism causes bones to grow longer, resulting in a very tall person with large feet and hands. it may cause:

• excessive sweating.
• severe or recurrent headaches.
• weakness.
• insomnia and other sleep disorders.
• delayed puberty in both boys and girls.
• irregular menstrual periods in girls.
• deafness.

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