Describe in detail how basic fibroblast growth factor is an exception to the universality genetic code
Human Basic Fibroblast Growth Factor Gene Encodes Four Polypeptides: Three Initiate Translation From non-AUG Codons.
It is an exception for universality ot genetic code.
Human basic fibroblast growth factor (bFGF) is an angiogenic polypeptide mitogen present in a wide variety of mesoderm- and neuroectoderm-derived tissues. bFGF cDNA and genomic clones predict a 17.8-kDa (155-amino acid) gene product based on the presence of a single putative translational initiator ATG codon. However, a bFGF protein isolated from human placenta contains two additional amino acids NH2-terminal to the predicted initiator methionine. We report here that the human cell line SK-HEP-1 coexpresses four molecular forms (17.8, 22.5, 23.1, and 24.2 kDa) of bFGF. The 17.8-kDa bFGF protein is translationally initiated at the previously predicted methionine (AUG) codon, whereas the 22.5-, 23.1-, and 24.2-kDa proteins initiate at unusual non-AUG codons. The higher molecular weight forms are colinear NH2-terminal extensions of the 18-kDa bFGF.
Describe in detail how basic fibroblast growth factor is an exception to the universality genetic code
Genetic Code The genetic code is what allows the string of nucleotides in our DNA to code for the sequence of amino acids that make up proteins. Briefly explain what this genetic code is in general and how it works. What is meant by the universality of the genetic code? Explain briefly what the advantages and disadvantages of this type of genetic code are to humans. ANSWER MUST BE ORIGINAL AND NO PLAGIARISM
Give an explanation why a mutation in the fibroblast growth factor receptor (FGFR) can disrupt embryonic development, even if the individual is heterozygous for this mutation.
Describe, in detail how erikson theory choice fulfills the genetic, social, and individual factors that create the total personality. Describe, in detail the origin principles, and assessment of validity and utility with regard to your particular personality theory
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Chapters 7, 8, 9 - Bacterial Growth & Metabolism (some chapter sections will be covered in lab) Prerequisite: Basic catabolic pathways (respiration and fermentation) and anabolic reactions (photosynthesis) BACTERIAL GROWTH AND CONTROL- Some of these topics will be covered in greater detail during lab Environmental Growth Factors 1. Discuss the specific role of quorum sensing in biofilm formation Control of Microbial Growth 2. Describe the methods used to control microbial growth 3. List the types of antibiotics that inhibit (a)...
We also discussed many errors that could occur in the genetic code (point mutations). Please briefly describe each of the four types of point mutations and how these relate to the four aspects of the genetic code described above: specificity, the genetic code is non-overlapping, continuous (no punctuation) and degenerate.