Question

Explain what is meant by the term 'minimal infectious dose' or LD50 and how it relates to the virulence of an organism

Answer 1

LD50

lethal dose 50 is dose at which 50% of the bacteria or animals will die .

LD50 is used in the toxicology studies to determine the impact of toxic subtances on the different organisms.it will compare and rank the toxicity of the substances.virulence sometimes measured by the LD50.This is the no of microbes to neccessary to kill 50% population infected with that microbe.The measurement of the virulence is relied on some quantifiable outcome on the host, such as mortality.