The receptors for your steroid hormones are on the inside of the cell, they are not...
The receptors for your steroid hormones are on the inside of the cell, they are not cell surface receptors. Propose an explanation for why the receptors for your steroid hormones can be on the inside of the cell and do not have to be cell surface receptors.
Homework Answers
Receptors for steroid and thyroid hormones are located inside target cells, in the cytoplasm or nucleus, and function as ligand-dependent transcription factors. That is to say, the hormone-receptor complex binds to promoter regions of responsive genes and stimulate or sometimes inhibit transcription from those genes.
Thus, the mechanism of action of steroid hormones is to modulate gene expression in target cells. By selectively affecting transcription from a battery of genes, the concentration of those respective proteins are altered, which clearly can change the phenotype of the cell.
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The receptors for your steroid hormones are on the inside of the
cell, they are not...
biochem Most hormones, such as peptide hormones, exert their effects by binding to cell surface receptors....
biochem
Most hormones, such as peptide hormones, exert their effects by binding to cell surface receptors. However, steroid hormones do so by binding to cytosolic receptors. How is this possible? Animals cannot synthesize linoleic acid (a precursor of arachidonic acid) and therefore must obtain this essential fatty acid from their diet. Explain why cultured animal cells can survive in the absence of linoleic acid.
Peptide hormones (such as insulin) must bind to receptors on the outside surfaces of their target...
Peptide hormones (such as insulin) must bind to receptors on the outside surfaces of their target cells before their signal is transmitted to the inside of the cell. In contrast, the receptors for steroid hormones (such as estradiol, shown below) are found inside cells OH H H HO Estradiol
Which type of receptors do steroid hormones generally employ? O G-protein coupled receptors O enzyme-coupled receptors...
Which type of receptors do steroid hormones generally employ? O G-protein coupled receptors O enzyme-coupled receptors nuclear receptors O ion-channel coupled receptors What type of cell response would take the longest amount of time (on the scale of minutes to hours) to execute? one that involves the release of secretory vesicles one that stimulate lamellipodia formation by regulating the actin cytoskeleton one that involves a change in gene expression one that uses a phosphorylation event to activate an enzyme
QUESTION 35 and their mechanism of action is to Thyroid hormones have receptors A. inside the...
QUESTION 35 and their mechanism of action is to Thyroid hormones have receptors A. inside the cell; activate transcription B. in the cell membrane; activate protein synthesis C. inside the cell; activate translation D. in the cell membrane: activate a protein
PES How do nonsteroid hormones differ from steroid hormones? Nonsteroid hormones act via a second messenger...
PES How do nonsteroid hormones differ from steroid hormones? Nonsteroid hormones act via a second messenger system steroid hormones do not use a second messenger system Nonsteroid hormones bind to cytoplasmic receptors, steroid hormones bind to plasma membrane receptors. The action of nonsteroid hormones never affects gene expression, the action of steroid hormones always affects gene expression Nonsteroid hormones are fat-soluble; steroid hormones are water-soluble. Nonsteroid hormones bind to acell's DNA:sterold hormones do not bind DNA U Question 5 1...
The following questions will require you to compare and contrast cell surface receptors and steroid hormone...
The following questions will require you to compare and contrast cell surface receptors and steroid hormone receptors. (a) Which type of receptor is more likely to have a hydrophobic ligand? (b) which type of receptor results in changes in gene transcription? Explain. (c) do peptide ligands usually travel to the nucleus with their receptors? (d) what is the benefit of a multistep signalling pathway over a single step signalling pathway?
Identify whether steroid hormones are water soluble or lipophilic. How are they transported in the blood?...
Identify whether steroid hormones are water soluble or lipophilic. How are they transported in the blood? Where on the cell are the receptors for these hormones located?
Need help on these questions ? 1.) Steroid hormones trigger transcription of target genes by... ...
Need help on these questions ? 1.) Steroid hormones trigger transcription of target genes by... a. activating the release of Ca+2 ions that bind to and activate transcription factors. b. activating a kinase cascade that results in the activation of a transcription factor for a set of genes. c. binding directly to DNA and stimulating transcription. d. binding to nuclear receptors that act as transcription factors for specific genes. 2.) Which type of cell-surface receptor(s), when...
What is the main difference between the activities of peptide hormones hormones? A. Peptide hormones do...
What is the main difference between the activities of peptide hormones hormones? A. Peptide hormones do not bind to receptors B. Peptide hormones bind to cell surface receptors C. Peptide hormones bind to stretches of RNA D. Steroid hormones bind to intracellular receptors but peptide hormone surface receptors E. Steroid hormones stimulate the release of second messengers but act directly by DNA Hypoglycemia inhibits secretion of which of the following hormones? A. growth hormone B. insulin C. epinephrine D. thyroid...
Steroid hormones exert their action by: a. crossing the plasma membrane and binding to nuclear receptors...
Steroid hormones exert their action by: a. crossing the plasma membrane and binding to nuclear receptors initiating or altering the expression of a gene b. binding to receptors located on the plasma membrane and initiating a secondary messenger effect active transport across the plasma membrane and attaching to cytoplasmic protein receptors d. crossing the plasma membrane and binding to cytoplasmic receptors Hypoglycemia is defined as a blood sugar: a. Less than 7.8 mmol/L b. Less than 2.5 mmol/L c. Greater...
biochem
Most hormones, such as peptide hormones, exert their effects by binding to cell surface receptors. However, steroid hormones do so by binding to cytosolic receptors. How is this possible? Animals cannot synthesize linoleic acid (a precursor of arachidonic acid) and therefore must obtain this essential fatty acid from their diet. Explain why cultured animal cells can survive in the absence of linoleic acid.
Peptide hormones (such as insulin) must bind to receptors on the outside surfaces of their target cells before their signal is transmitted to the inside of the cell. In contrast, the receptors for steroid hormones (such as estradiol, shown below) are found inside cells OH H H HO Estradiol
Which type of receptors do steroid hormones generally employ? O G-protein coupled receptors O enzyme-coupled receptors nuclear receptors O ion-channel coupled receptors What type of cell response would take the longest amount of time (on the scale of minutes to hours) to execute? one that involves the release of secretory vesicles one that stimulate lamellipodia formation by regulating the actin cytoskeleton one that involves a change in gene expression one that uses a phosphorylation event to activate an enzyme
QUESTION 35 and their mechanism of action is to Thyroid hormones have receptors A. inside the cell; activate transcription B. in the cell membrane; activate protein synthesis C. inside the cell; activate translation D. in the cell membrane: activate a protein
PES How do nonsteroid hormones differ from steroid hormones? Nonsteroid hormones act via a second messenger system steroid hormones do not use a second messenger system Nonsteroid hormones bind to cytoplasmic receptors, steroid hormones bind to plasma membrane receptors. The action of nonsteroid hormones never affects gene expression, the action of steroid hormones always affects gene expression Nonsteroid hormones are fat-soluble; steroid hormones are water-soluble. Nonsteroid hormones bind to acell's DNA:sterold hormones do not bind DNA U Question 5 1...
What is the main difference between the activities of peptide hormones hormones? A. Peptide hormones do not bind to receptors B. Peptide hormones bind to cell surface receptors C. Peptide hormones bind to stretches of RNA D. Steroid hormones bind to intracellular receptors but peptide hormone surface receptors E. Steroid hormones stimulate the release of second messengers but act directly by DNA Hypoglycemia inhibits secretion of which of the following hormones? A. growth hormone B. insulin C. epinephrine D. thyroid...
Steroid hormones exert their action by: a. crossing the plasma membrane and binding to nuclear receptors initiating or altering the expression of a gene b. binding to receptors located on the plasma membrane and initiating a secondary messenger effect active transport across the plasma membrane and attaching to cytoplasmic protein receptors d. crossing the plasma membrane and binding to cytoplasmic receptors Hypoglycemia is defined as a blood sugar: a. Less than 7.8 mmol/L b. Less than 2.5 mmol/L c. Greater...
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