Question

1. Which of the following is true of the processes that occur during fatty acid synthesis?

a.	The second step uses NADPH to form an alcohol.
b.	The forth step uses NADPH to reduce a C=C double bond, thus forming a saturated acyl molecule attached to the ACP.
c.	The third step removes a water molecule to form a C=C double bond
d.	All of these are true.
e.	An immediate product of the condensation reaction is a beta-ketoacyl group extended by two carbons.

Answer 1

d.) ALL OF THESE ARE TRUE.

Synthesis of fatty acids occur in the cytosol of animals. It involves the stepwise addition of 2 carbon units which are supplied by Acetyl coA. These 2 subunits are Acetyl ACP and Malonyl ACP. Further the reactions occur step wise. In the end of the cycle the cycle repeats itself that is called elongation of fatty acids. All of the above options are correct, the main reactions are Condensation, Reduction and dehydration.  

Acetyl-Acp + malonyl -Ace fcondensation] I | Acetoacyl-ACP] B-ketoget-Ace Les MADDE (Reduction] D-3-hydroxyacyl-ACP ß-Hydroxyacyl- lyto Acp Reductase tize (Denyaration) Crotonyl- ALPI 2,3 trans-Enoy! I NADPH Alp-reductase to NADP+ 1 Butyryl- Alp Scanned with CamScanner