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QUESTION 1 Match the 1-3 word answers for the following statements related to fatty acid oxidation...
Fatty acid oxidation occurs in the mitochondrial matrix. However, long-chain fatty acyl-CoA molecules cannot cross...
Fatty acid oxidation occurs in the mitochondrial matrix. However, long-chain fatty acyl-CoA molecules cannot cross the inner membrane to enter the matrix. The carnitine shuttle system transfers the acyl group from CoA to carnitine, which can enter the mitochondrial matrix.
Label the enzymes and compounds of the carnitine shuttle system. The following enzyme abbreviations are used: carnitine acyltransferase I, CAT1; mitochondrial carnitine acyltransferase II, CAT2; and carnitine/acylcarnitine translocase (carnitine carrier protein), CAT.
What changes in fatty acid metabolism would result from a mutation in the muscle carnitine acyltransferase...
What changes in fatty acid metabolism would result from a mutation in the muscle carnitine acyltransferase I in which the mutant protein has lost its affinity for malonyl-CoA but not its catalytic activity? A. Fatty acid synthesis in the mitochondria and fatty acid oxidation in the cytosol could occur simultaneously. B. Fatty acid synthesis in the cytosol and fatty acid oxidation in the mitochondria could occur simultaneously. C. Synthesis of malonyl carnitine could only occur at high malonyl-CoA concentration. D....
Identify and briefly discuss each mechanism ensuring against simultaneous fatty acid synthesis and oxidation in the same cell. Match the words in the left column to the appropriate blanks in the sente...
Identify and briefly discuss each mechanism ensuring against simultaneous fatty acid synthesis and oxidation in the same cell. Match the words in the left column to the appropriate blanks in the sentences on the right. hydrolase acetyl-CoAs synthesis activates citrate pyruvate inhibits synthetase oxidation malonyl-CoA fatty acyl-CoAs carboxylase glucagon insulin A key intermediate in fatty acid synthesis,____, ______ carnitine acyltransferase I, thereby blocking the entry of fatty acyl units into the mitochondrion for oxidation. The substrates for fatty acid oxidation,...
EOS Fatty acid metabolism: Q1 1 point possible (graded) Fatty acid synthase is primed with two...
EOS Fatty acid metabolism: Q1 1 point possible (graded) Fatty acid synthase is primed with two molecules at the beginning of odd-chain fatty acid synthesis. What are these TWO molecules? Propionyl-COA Palmitoyl-CoA Malonyl-CoA Acetyl-COA I Acyl-Coa union How many molecules of malonyl-CoA would be invested to synthesize one molecule of the fatty acid shown above? How many molecules of NADPH would be invested to synthesize one molecule of the fatty acid shown above? How many molecules of ATP would be...
An activated fatty acid (acyl-CoA) can be transported into the mitochondria for b-oxidation or remain in...
An activated fatty acid (acyl-CoA) can be transported into the mitochondria for b-oxidation or remain in the cytosol for lipogenesis to produce a triacylglycerol. What regulates the fate of this acyl-CoA? A. the amount of acyl-CoA in the mitochondria B. the amount of acyl-carnitine in the mitochondria C. the amount of NADH in the cytoplasm D. the amount of malonyl CoA in the cytoplasm E. the amount of acetyl-CoA in the cytoplasm
Complete the sentences to explain why long chain fatty acids cannot pass the mitochondrial membrane via...
Complete the sentences to explain why long chain fatty
acids cannot pass the mitochondrial membrane via diffusion, and the
mechanism by which the cells transport them.
duction of Energy via Fatty Acid Oxidation CPT II mitochondrial matrix large CPT I inner mitochondrial Long-chain fatty acids have an alkyl chain of more than 10 carbon atoms. Fatty acids with alkyl chains of this length are characterized as size. This length decreases their ability to cross the lipid bilayer of the mitochondrial...
1. Which of the following is true? a. The main rate-limiting step for fatty acid breakdown...
1. Which of the following is true? a. The main rate-limiting step for fatty acid breakdown is the transfer of the fatty acyl group to carnitine, with release of CoA. b. Elongase activity is an enzyme functionality of fatty acid synthase that adds 2-carbon acetyl groups to increase the length of palmitate. c. Oligomycin directly inhibits Complex I in the electron transport chain d. Squalene synthase catalyzes the rate-limiting step of fatty acid synthesis.
Complete the sentences to correctly describe steps in fatty acid synthesis. Put the terms to the...
Complete the sentences to correctly describe steps in fatty acid synthesis. Put the terms to the appropriate blanks. Some terms will not be used, and some will be used more than once. Fatty acid synthesis begins with a preparatory step in which ____________ is transferred from ___________ to the ___________. However, it cannot pass through the membrane, so it is transported as ___________, which is cleaved to ____________ and ____________. In the cytosol, acetyl CoA is converted to ____________, a...
7- Oxidation of fatty acids occure in: A. Mitochondria B. Endoplasmic reticulum C. Lysosome D. Cell...
7- Oxidation of fatty acids occure in: A. Mitochondria B. Endoplasmic reticulum C. Lysosome D. Cell Membrane 8- End product of B-oxidation of fatty acid with even number of carbon atoms is: A- a-keto glutarate B- Propionyl CoA C- Acetoacetyl CoA D- Acetyl CoA 9- How many ATP molecules produces from B-oxidation of palmitylCoA? A.109 B. 129 C. 24 D. 38 ● 10- How many ATP molecules produces from one turn of B-oxidation ? A- 109 B. 129 C. 5 ...
Question 1. Calculate the numbers of acetyl-CoA molecules produced when a fatty acid with 14 carbons...
Question 1. Calculate the numbers of acetyl-CoA molecules produced when a fatty acid with 14 carbons after undergoing beta-oxidation? Question 2. How many a) cycles of beta-oxidation will a fatty acid with 14 carbons undergo? Explain briefly. b)? How many acetyl-CoA molecules ? explain briefly? Question 3. Consider the synthesis of fatty acids: Answer the flowing: True or False: a) CoA carries intermediate b) Acetyl-CoA donates two carbon atoms c) Malonyl-CoA donates two carbon atoms d) The reverse of fatty...
Fatty acid oxidation occurs in the mitochondrial matrix. However, long-chain fatty acyl-CoA molecules cannot cross the inner membrane to enter the matrix. The carnitine shuttle system transfers the acyl group from CoA to carnitine, which can enter the mitochondrial matrix.
Label the enzymes and compounds of the carnitine shuttle system. The following enzyme abbreviations are used: carnitine acyltransferase I, CAT1; mitochondrial carnitine acyltransferase II, CAT2; and carnitine/acylcarnitine translocase (carnitine carrier protein), CAT.
EOS Fatty acid metabolism: Q1 1 point possible (graded) Fatty acid synthase is primed with two molecules at the beginning of odd-chain fatty acid synthesis. What are these TWO molecules? Propionyl-COA Palmitoyl-CoA Malonyl-CoA Acetyl-COA I Acyl-Coa union How many molecules of malonyl-CoA would be invested to synthesize one molecule of the fatty acid shown above? How many molecules of NADPH would be invested to synthesize one molecule of the fatty acid shown above? How many molecules of ATP would be...
Complete the sentences to explain why long chain fatty
acids cannot pass the mitochondrial membrane via diffusion, and the
mechanism by which the cells transport them.
duction of Energy via Fatty Acid Oxidation CPT II mitochondrial matrix large CPT I inner mitochondrial Long-chain fatty acids have an alkyl chain of more than 10 carbon atoms. Fatty acids with alkyl chains of this length are characterized as size. This length decreases their ability to cross the lipid bilayer of the mitochondrial...
Question 1. Calculate the numbers of acetyl-CoA molecules produced when a fatty acid with 14 carbons after undergoing beta-oxidation? Question 2. How many a) cycles of beta-oxidation will a fatty acid with 14 carbons undergo? Explain briefly. b)? How many acetyl-CoA molecules ? explain briefly? Question 3. Consider the synthesis of fatty acids: Answer the flowing: True or False: a) CoA carries intermediate b) Acetyl-CoA donates two carbon atoms c) Malonyl-CoA donates two carbon atoms d) The reverse of fatty...
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