1. Which of the following is true? a. The main rate-limiting step for fatty acid breakdown...
1. Which of the following is true?
a. The main rate-limiting step for fatty acid breakdown is the transfer of the fatty acyl group to carnitine, with release of CoA.
b. Elongase activity is an enzyme functionality of fatty acid synthase that adds 2-carbon acetyl groups to increase the length of palmitate.
c. Oligomycin directly inhibits Complex I in the electron transport chain
d. Squalene synthase catalyzes the rate-limiting step of fatty acid synthesis.
Homework Answers
1a.This is true.The main rate limitation step for fatty acid breakdown is the transfer of fatty acyl group to carnitine, with release of CoA
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1. Which of the following is true?
a. The main rate-limiting step for fatty acid breakdown...
QUESTION 1 Match the 1-3 word answers for the following statements related to fatty acid oxidation...
QUESTION 1 Match the 1-3 word answers for the following statements related to fatty acid oxidation and fatty acid synthesis. In animal cells, fatty acid synthesis carried A. Cytosol out in the B. Mitochondrial matrix. The site of B-oxidation in the cell is C. Malonyl-CoA Intermediate in fatty acid synthesis that D. Complex I inhibits carnitine acyltransferase I, thus regulating fatty acid oxidation. E. Carnitine in the third step of B-0&1&atiov, electrons are NADPH transferred to NAD+; NADH then donates...
Need help with both questions, thank you! Question 13 The committed step of fatty acid synthesis...
Need help with both questions, thank you!
Question 13 The committed step of fatty acid synthesis is catalyzed by the enzyme acetyl CoA carboxylase. Which of the following accurately describes this enzyme? None of the choices is correct. All of the choices are correct Phosphorylation of the enzyme inhibits its activity. The inhibited enzyme can be stimulated by allosteric regulation of citrate. The dephosphorylated enzyme is active. Question 14 Formation of this molecule is the committed step of fatty acid...
Identify and briefly discuss each mechanism ensuring against simultaneous fatty acid synthesis and oxidation in the same cell. Match the words in the left column to the appropriate blanks in the sente...
Identify and briefly discuss each mechanism ensuring against simultaneous fatty acid synthesis and oxidation in the same cell. Match the words in the left column to the appropriate blanks in the sentences on the right. hydrolase acetyl-CoAs synthesis activates citrate pyruvate inhibits synthetase oxidation malonyl-CoA fatty acyl-CoAs carboxylase glucagon insulin A key intermediate in fatty acid synthesis,____, ______ carnitine acyltransferase I, thereby blocking the entry of fatty acyl units into the mitochondrion for oxidation. The substrates for fatty acid oxidation,...
Mention if the following statements are false or true and justify your answer a. Biotin is...
Mention if the following statements are false or true and justify your answer a. Biotin is required for the activity of fatty acid synthase b. The reaction of condensation in the synthesis of fatty acids is enhanced by the decarboxylation of malonyl-CoA c. The synthesis of fatty acids does not depend on ATP d. Palmitate is the final product of fatty acid synthase e. All the activities of the enzyme required for the synthesis of fatty acids in mammals are...
Complete the sentences to correctly describe steps in fatty acid synthesis. Put the terms to the...
Complete the sentences to correctly describe steps in fatty acid synthesis. Put the terms to the appropriate blanks. Some terms will not be used, and some will be used more than once. Fatty acid synthesis begins with a preparatory step in which ____________ is transferred from ___________ to the ___________. However, it cannot pass through the membrane, so it is transported as ___________, which is cleaved to ____________ and ____________. In the cytosol, acetyl CoA is converted to ____________, a...
which of the following is True about beta oxidization of fatty acid (true or false) a*...
which of the following is True about beta oxidization of fatty acid (true or false) a* to occur in mammalian cell fatty acids must first be converted to acyl-coa which is then converted to acyl camitine for transport into mitochondria b*. full oxidization of fatty acid will lead to more reduced electron carries NADH and FADH2 as compared to full oxidization of carbohydrate of the same length c*. production of acetyl coa from fatty acid includes substrate level phosphorylation step...
Indicate whether the following statements are true or false. Justify your answer. a. ( 3 pts)...
Indicate whether the following statements are true or false. Justify your answer. a. ( 3 pts) _____ Acetyl- CoA carboxylase is activated by palmitoyl- CoA. b. (3 pts) ______ During the synthesis of palmitate in liver cells, the addition of malonyl- CoA to fatty acid synthase elongates the growing chain by three carbons. c. ( 3 pts) ______ Lipoprotein lipase is an intracellular enzyme.
EOS Fatty acid metabolism: Q1 1 point possible (graded) Fatty acid synthase is primed with two...
EOS Fatty acid metabolism: Q1 1 point possible (graded) Fatty acid synthase is primed with two molecules at the beginning of odd-chain fatty acid synthesis. What are these TWO molecules? Propionyl-COA Palmitoyl-CoA Malonyl-CoA Acetyl-COA I Acyl-Coa union How many molecules of malonyl-CoA would be invested to synthesize one molecule of the fatty acid shown above? How many molecules of NADPH would be invested to synthesize one molecule of the fatty acid shown above? How many molecules of ATP would be...
As we will see in our discussion of lipid metabolism, fatty acid breakdown generates a large...
As we will see in our discussion of lipid metabolism, fatty acid breakdown generates a large amount of acetyl-CoA. Part A Predict the effect of a large amount of acetyl-CoA on the activity of pyruvate dehydrogenase and the rate of glycolysis. Note: pyruvate dehydrogenase is the enzyme that catalyzes the formation of acetyl-CoA from pyruvate. O Both pyruvate dehydrogenase activity and the rate of glycolysis will decrease. O The rate of glycolysis will increase, thereby, leading to an increase in...
1. What prevents fatty acid synthesis and fatty acid degradation from occurring at the same time?...
1. What prevents fatty acid synthesis and fatty acid degradation from occurring at the same time? 2. Name the function of the following molecules or enzyme. a. bile salts b. carnitine c. acetyl-CoA carboxylase (ACC) 3. Describe the biochemical processes associated with weight loss and weight gain.
QUESTION 1 Match the 1-3 word answers for the following statements related to fatty acid oxidation and fatty acid synthesis. In animal cells, fatty acid synthesis carried A. Cytosol out in the B. Mitochondrial matrix. The site of B-oxidation in the cell is C. Malonyl-CoA Intermediate in fatty acid synthesis that D. Complex I inhibits carnitine acyltransferase I, thus regulating fatty acid oxidation. E. Carnitine in the third step of B-0&1&atiov, electrons are NADPH transferred to NAD+; NADH then donates...
Need help with both questions, thank you!
Question 13 The committed step of fatty acid synthesis is catalyzed by the enzyme acetyl CoA carboxylase. Which of the following accurately describes this enzyme? None of the choices is correct. All of the choices are correct Phosphorylation of the enzyme inhibits its activity. The inhibited enzyme can be stimulated by allosteric regulation of citrate. The dephosphorylated enzyme is active. Question 14 Formation of this molecule is the committed step of fatty acid...
EOS Fatty acid metabolism: Q1 1 point possible (graded) Fatty acid synthase is primed with two molecules at the beginning of odd-chain fatty acid synthesis. What are these TWO molecules? Propionyl-COA Palmitoyl-CoA Malonyl-CoA Acetyl-COA I Acyl-Coa union How many molecules of malonyl-CoA would be invested to synthesize one molecule of the fatty acid shown above? How many molecules of NADPH would be invested to synthesize one molecule of the fatty acid shown above? How many molecules of ATP would be...
As we will see in our discussion of lipid metabolism, fatty acid breakdown generates a large amount of acetyl-CoA. Part A Predict the effect of a large amount of acetyl-CoA on the activity of pyruvate dehydrogenase and the rate of glycolysis. Note: pyruvate dehydrogenase is the enzyme that catalyzes the formation of acetyl-CoA from pyruvate. O Both pyruvate dehydrogenase activity and the rate of glycolysis will decrease. O The rate of glycolysis will increase, thereby, leading to an increase in...
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