Question

Which of the following statements about eukaryotic activator proteins is false? Choose one: A. They stimulate transcriptional initiation by opening up the double helix. * B. They stimulate transcription initiation by recruiting proteins that modify chromatin structure. C. They stimulate transcription initiation by aiding in the assembly of general transcription factors and RNA polymerase at the promoter. D. They stimulate transcription initiation by promoting the assembly of a transcription initiation complex at the promoter.

Answer 1

The following statement that is false about eukaryotic activator proteins is-

A- Eukaryotic activator proteins stimulate transcription initiation by opening up the double helix.

This statement is false because the protein that helps in opening up the double helix is DNA helix. Eukaryotic activator proteins are responsible for stimulating the initiation by calling out for the assembly of transcription initiation complex at the promoter region. This is done by RNA polymerase which is the core enzyme and has 5 core subunits. The activator proteins also allows the assembly of general transcription factors and RNA polymerase. RNA pol binds with sigma70 factor to allow initiation of transcription. They also signal proteins that allow certain proteins to alter the chromatin structure.

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