1. Which of the following is a tumor suppressor gene (or the product of a tumor suppressor gene)? Select all answers that apply.
A. Raf
B. Her2 receptor
C. PTEN
D. INK4a
E. p53
2. Which of the following is a proto-oncogene (or the product of a proto-oncogene)? Select all answers that apply.
A. APC
B. EGFR
C. bcl-2
D. RB
E. ptc1
Answer :
1. (E). P53 is a tumor suppressor gene.
2. (B). EGFR is a proto-oncogene.
1. Which of the following is a tumor suppressor gene (or the product of a tumor...
Q1)canser start when: 1:only tumor suppressor gene is mutated. 2:only proto-oncogene is mutated. 3:proto-oncogene and tumor suppressor gene are mutated at the sane time 4:proto-oncogene and tumor suppressor gene are not mutated at the sane time . which is correct ?
Classify each of the following into whether it represents a nonmutated proto-oncogene or a tumor suppressor gene. Proto-Oncogenes Tumor Supressor Genes Inhibitors of p53 Apoptosis is restrained Apoptosis is promoted Eventually become inactive Sufficient cyclin Inhibitors of cyclin Eventually become oncogenes Promoters of p53 Cell cycle is restrained Cell cycle occurs normally
Genetics
Which of the following statements best describes P53? - It is a tumor-suppressor. It is a proto-oncogene. OP53 GOF alters the chromatin state in cancer cells. O All of the answers are true. In the maternal care active learning session, the paper demonstrated that the of the pups was dependent upon the of the mother. Genotype/ CpG methylation levels CpG methylation levels/ age CpG methylation levels/ phenotype CpG methylation levels/ genotype
Indicate whether each of the following descriptions applies to an oncogene, a proto-oncogene, or a tumor suppressor gene. Some descriptions may apply to more than one of these gene types. Drag the gene types on the left to the appropriate blanks on the right to match the descriptions. Gene types can be used once, more than once, or not at all. Reset Help oncogene - gene(s) whose presence can cause cancer. proto-oncogene -gene(s) whose absence can cause cancer. tumor suppressor...
Which of the following is a false statements about tumor suppressor genes? Gene amplification (duplication) of a tumor suppressor gene is less likely to result in cancer than gene amplification of a proto-onocogene. Individuals with a single normal copy of a tumor suppressor gene are more prone to cancer than those with two normal copies. Inactivation of tumor suppressor genes can lead to enhanced cell survival and cell proliferation. Epigenetic changes that silence tumor suppressor genes would not lead to...
Bookmarks Window Help proteins would Which of the fo -CELL BIOLOGY (BIOL408005)-1192 Question Completion Status: Which of the following proteins would you classify as a tumor suppressor (a protein that prevents cancerous uncontrolled growth)? the kinase Wee1 APC the phosphatase cdc25 M-CDK QUESTION 10 Which of the following proteins would you classify as a proto-oncogene (a protein that can promote uncontrolled growth)? the phosphatase cdc25 the kinase Wee1 the anaphase inhibitor the cohesion protein Click Save and Submit to save...
Label the following as either proto-oncogene, oncogene or tumor suppressor 3. A gene that initiates apoptosis when DNA damage occurs a. b. A gene that initiates the transition from G1 to S phase A gene that inhibits the transition from G1 to S phase c. d. A gene that promotes cell growth, combined with a hyperactive promoter How would methylation of the promoter of the gene in question 3c affect the cell? Be specific using what you know about the...
A tumor suppressor gene is best described by which of the following? a. when it is expressed, the gene suppresses viral genes from being expressed b. a gain-of-function mutation lead to uncontrolled proliferation c. when it is express, the gene induces tumor formation d. a loss-of-function mutation leads to uncontrolled proliferation e. when it is expressed, the gene specifically blocks the G 1/S checkpoint.
Polycyclic aromatic hydrocarbons in tobacco smoke are potent carcinogens because they preferentially bind to, and trigger base substitutions, in the A. Ras gene. B. p53 gene. C. Raf gene. D. PTEN gene. E. EGF receptor gene.
Retinoblastoma (resulting in eye tumor) results from inactivation of Rb gene, a tumor suppressor. A).List the molecular events that lead to the development of hereditary retinoblastoma? ________________________________________________________________________________________________________________________________________________________________________________________________ B). How the development of sporadic retinoblastoma will be different from the hereditary one? Mention the molecular steps that will be unique for the sporadic retinoblastoma? _________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________ C). Is the loss of Rb function dominant or recessive and why? ________________________________________________________________________________________________________________________________________________________________________________________________ D). Knowing the Rb binds to E2F, which is transcription factor activating expression...