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Polycyclic aromatic hydrocarbons in tobacco smoke are potent carcinogens because they preferentially bind to, and trigger...

Polycyclic aromatic hydrocarbons in tobacco smoke are potent carcinogens because they preferentially bind to, and trigger base substitutions, in the

A. Ras gene.

B. p53 gene.

C. Raf gene.

D. PTEN gene.

E. EGF receptor gene.

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Answer #1

Correct answer is option B - p53 gene

Explanation: Polycyclic aromatic hydrocarbons (PAHs) which are found in cigarette smoke causes transitions type of base substitutions . for example G→A transitions in p53 gene is frequently observed in may types of cancers including lung cancers which are induced by smoking.

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