Discuss the advantages of using aldehydes without alpha-hydrogens in cross aldol condensation.
Discuss the advantages of using aldehydes without alpha-hydrogens in cross aldol condensation.
Consider the following crossed aldol condensation. Which statement explains why a single cross condensation product is formed? 2,2-dimethylcyclohexanone "CH₃ H₂C, CH, H NaOCH.CH H3C thanol benzaldehyde 2,2-Dimethylcyclohexanone has only one alpha carbon which can form an enolate. Benzaldehyde has no hydrogens attached to the alpha carbon which eliminates the self-condenstation reaction. 2,2-Dimethylcyclohexanone is sterically hindered which limits the self-condenstation reaction. All of the above
Which of the compounds below have no alpha- hydrogens? What does this mean for the aldol condensation? Just give the letters of the compounds._____________acetone 2- butanone diphenyl ketone 2,3-dimethy 1-1-phenyl-1-propanone cyclobutanone
There are several variations of the Aldol reaction. Which of the following types of reactants leads to only one possible product with the Aldol condensation reaction? a. Two different aldehydes with alpha-hydrogens are able to form a single aldol condensation product. b. Two different ketones with alpha-hydrogens are able to form a single aldol condensation product. c. Any aldehyde and ketone mixed together can react to form a single condensation product. d. Any pair of aldehyde or ketone reactants where...
QUESTION 1 Which of the following will not undergo an aldol condensation reaction? butanal C 2-methylbutanal C 2,2-dimethylbutanal 3,3-dimethyl-2-butanone QUESTION 2 Which of the following constitutes a difference between an aldol and a Claisen condensation? basic conditions Ctetrahedral intermediate Cenolate ion formation protonation of the intermediate QUESTION 3 The product of an aldol condensation reaction is generally favored if Can unsymmetrical ketone and aldehyde are used Can unsymmetrical ester and ketone are used Cone of the carbonyl partners contains no...
5. In an aldol condensation why must there be an H atom on the alpha carbon adjacent to a carbonyl group of one of the reacting compounds? (3 marks)
QUESTION 33 2 points ($18.7) What is the product of the following crossed aldol condensation? (Complete aldol reactions using two different aldehydes or ketones.) Reagents: acetyl aldehyde + p-chlorobenzaldehyde (no alpha hydrogen) + NaOH a strong base + H20 and heat.) HOA o oo QUESTION 34 2 points (518.7) Which compound, in a reaction with the ketone below, would produce the fewest side products? (Identify which aldol reactions will proceed in high yield). Reagents: starting material acetone + (1) NaOH...
Aldol Condensation: 1) What is the purpose of using NaOH solution in this Aldol condensation? 2) Why acetic acid is used to wash the solid on the fiter? 3) Draw the structure of the product from the reaction: NaOH H +Acetone in ethanol
The following Aldol Condensation produces a mixture of SIX -alpha, beta-unsaturated carbonyl products. DRAW the structure of all Six the alpha, beta-unsaturated products obtained.
Rheosmin is a saturated ketone obtained from an alpha,beta-unsaturated ketone (a crossed aldol condensation product) which is capable of undergoing hydrogenation to yield a saturated ketone (Rheosmin). Using this technique, identify the reagents needed to prepare Rheosmin via crossed aldol reaction. Rheosmin 4-(4-hydroxyphenyl)butan-2-one
Discuss how microwave irradiation was used to accelerate the reaction of intramolecular aldol condensation of 2,5-hexanedione using 0.05 M NaOH.