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Why does atherosclerosis lead to a heart attack or stroke? It promotes inflammation, which injures heart...

Why does atherosclerosis lead to a heart attack or stroke?
It promotes inflammation, which injures heart or brain tissue.
It causes oxidized low-density lipoproteins to attack heart and brain cells, depriving them of oxygen and nutrients.
It reduces or blocks blood flow to the tissues below the clogged artery, resulting in tissue death.
It causes blood vessels to be so damaged, they stop delivering blood to cells in the brain and heart.
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Answer #1

The correct answer to this question is option three:

It reduces or blocks blood flow to the tissues below the clogged artery, resulting in tissue death.

Atherosclerosis is the narrowing of the arteries due to plaque build-up inside the arterial walls.
Arteries are the blood vessels that carry blood and oxygen from the heart to the rest of the body. With age, Endothelium of the arteries may get damaged allowing harmful cholesterol, fats, and calcium to aggregate in the arteries and form plaque inside the walls causing narrowing of the arteries. The blood and oxygen supply to various body parts get disrupted because of this blockage resulting in their damage.

Sometimes, parts of this plaque gets broken and may stick with each other causing blockages. Massive blockage may even lead to blood clots causing a stroke, heart attack and other life-threatening conditions.

The other options are not suitable answers and only option 3 makes proper sense in relation to Atherosclerosis.

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