If there is a mutation in the gene for collagen, such as the one involved in...
If there is a mutation in the gene for collagen, such as the one involved in Ehlers-Danlos syndrome, and the individual produces defective collagen, how would it affect coagulation?
a. The syndrome affects the clotting factors and platelet aggregation.
b. The syndrome leads to hyper-coagulation of blood.
c. Coagulation is not affected because collagen is not required for coagulation.
d. The syndrome occurs due to the breakdown of platelets.
Homework Answers
Answer is c. Coagulation is not affected because collagen is not required for coagulation.
Platelet function and coagulation are usually normal in patients with Ehlers-Danlos syndrome, despite a tendency of bruising and increased bleeding further indicating the defective structural integrity of skin and blood vessels.
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