Question

b. Which structures must have become leaky for contraction to occur?
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Answer #1

The contraction occurs in a cascade manner. So, contraction needs a few steps to occur properly. The structure which needs to leaky is the sarcoplasmic reticulum which stores calcium ions in it.

When a stimulus reaches the sarcolemma and propagated through the T tubule, the sarcoplasmic reticulum adjacent to it reacts to it. The DHPR and Ryanodine receptors facilitate the release of Calcium into the sarcomere. Which then binds to troponin and causes a conformational change that causes tropomyosin to unmask the binding site.

So, the structure that has to be leaky is the Sarcoplasmic Reticulum.

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