A woman in a high risk population has the gene for sickle-cell is 1/10. If the...
A woman in a high risk population has the gene for sickle-cell is 1/10. If the woman has the gene each of her children has the probability 1/2 of having the disease, if she does not the probability is zero. If the woman has 3 sons without sickle-cell what is the probability that she carries the sickle-cell gene?
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A woman in a high risk population has the gene for sickle-cell
is 1/10. If the...
A woman has a father with sickle-cell anemia, which is an autosomal recessive trait. She does not have symptoms of sickle-cell anemia. What is her genotype? (0.5 marks) b) She is about to start a fami...
A woman has a father with sickle-cell anemia, which is an autosomal recessive trait. She does not have symptoms of sickle-cell anemia. What is her genotype? (0.5 marks) b) She is about to start a family, and she knows that her partner’s mother has sickle-cell anemia, but he does not have the disease himself. What is the probability of them having a child with sickle-cell anemia? Demonstrate this using a Punnett square. (2.5 marks) c) If they have three children,...
A man who is “normal” (has no sickle cell allele) has children with a woman who...
A man who is “normal” (has no sickle cell allele) has children with a woman who is immune to malaria. What percentage of their children would also be immune to malaria? What percentage would have sickle cell disease? Show a Punnett square using the genotypes/alleles.
Question 1: Question 2: You are a population geneticist interest in the frequency of the sickle-cell...
Question 1:
Question 2:
You are a population geneticist interest in the frequency of the sickle-cell allele in a small town in Sudan. From hospital records you know that people in the previous generation had 4% incidence of sickle-cell anemia. Assuming Hardy-Weinberg equilibrium, what is the expected frequency of the sickle-cell allele in the current generation, and what is the predicted frequency of heterozygotes in the population? Consider a woman who suffers from Menkes Disease, an X-linked recessive disease. Her...
Use the following information to answer the next two questions. Sickle cell anemia is a disease...
Use the following information to answer the next two questions. Sickle cell anemia is a disease that is caused by a mutation in the gene that produces haemoglobin. Hemoglobin carries oxygen in red blood cells. The HbA allele produces normal hemoglobin and the HbS allele produces haemoglobin that sticks together and causes red blood cells to sickle. Heterozygous individuals (HbAHbS) produce both normal and "sickle" hemoglobin so the HbA and HbS alleles are codominant. Heterozygotes do not develop sickle cell...
A woman with sickle cell trait is four months pregnant, and knows that her fetus is...
A woman with sickle cell trait is four months pregnant, and knows that her fetus is homozygous for the βs gene. She wants to visit her mother in Denver but worries whether the decrease in oxygen pressure there will cause the fetus to have a sickle cell crisis. What do you tell her?
Problem 1 [9 points]. Sickle cell disease (SCD) is a classification of disorders that affect red...
Problem 1 [9 points]. Sickle cell disease (SCD) is a classification of disorders that affect red blood cells such that they distort them into the shape of a crescent or sickle shape. Data was collected on age and prevalence of sickle cell disease of children, which we will use to examine any potential association between age and disease prevalance. The probabilities of each category can be estimated from the data by taking the relative frequency. For example, the probability that...
blood disease that is extremely severe It is particularly common in 11. (4 points) Sickle-cell anemia...
blood disease that is extremely severe It is particularly common in 11. (4 points) Sickle-cell anemia is a hereditary chronic bl when an individual carries two copies of the defective gene countries plagued by malaria, a parasitic infection transmitt tested 543 children for the sickle-cell gene and also for malaria. 136 children with the sickle-cell gene, 36 children had severe n consisted of 407 children without the sickle-cell gene, infections. A 99% confidence interval for p-p , the difference in...
Two parents come to see you for genetic counseling. Dad is sickle cell carrier (sickle cell...
Two parents come to see you for genetic counseling. Dad is sickle cell carrier (sickle cell is a recessive genetic disease) and has a normal cholesterol. Mom is also a carrier for sickle cell and has struggled with high cholesterol, and a test by her doctor recently showed that she is heterozygous for hypercholesterolemia (hypercholesterolemia is a genetic disease that shows incomplete dominance). What are the odds of them producing a child with sickle cell disease?-------A child who is a...
3. Sickle-cell disease is a genetic condition caused by an autosomal recessive allele which al- fects...
3. Sickle-cell disease is a genetic condition caused by an autosomal recessive allele which al- fects one in every 500 African American children born in the U.S. One in every ten African Americans is a carrier for the recessive allels. Although sickle cell disease is caused by a single human gene, it is expressed through many different effects throughout the body. The presence of a recessive sickle-cell allele in humans causes the red blood cells to produce abnormal hemoglobin protein...
In the general population, one woman in eight will develop breast cancer. Research has shown that...
In the general population, one woman in eight will develop breast cancer. Research has shown that 1 woman in 600 carries a mutation of the BRCA gene. Seven out of 10 women with this mutation develop breast cancer. Find the probability that a randomly selected woman will develop breast cancer given that she has a mutation of the BRCA gene. (Round to one decimal place as needed.)
Question 1:
Question 2:
You are a population geneticist interest in the frequency of the sickle-cell allele in a small town in Sudan. From hospital records you know that people in the previous generation had 4% incidence of sickle-cell anemia. Assuming Hardy-Weinberg equilibrium, what is the expected frequency of the sickle-cell allele in the current generation, and what is the predicted frequency of heterozygotes in the population? Consider a woman who suffers from Menkes Disease, an X-linked recessive disease. Her...
Problem 1 [9 points]. Sickle cell disease (SCD) is a classification of disorders that affect red blood cells such that they distort them into the shape of a crescent or sickle shape. Data was collected on age and prevalence of sickle cell disease of children, which we will use to examine any potential association between age and disease prevalance. The probabilities of each category can be estimated from the data by taking the relative frequency. For example, the probability that...
blood disease that is extremely severe It is particularly common in 11. (4 points) Sickle-cell anemia is a hereditary chronic bl when an individual carries two copies of the defective gene countries plagued by malaria, a parasitic infection transmitt tested 543 children for the sickle-cell gene and also for malaria. 136 children with the sickle-cell gene, 36 children had severe n consisted of 407 children without the sickle-cell gene, infections. A 99% confidence interval for p-p , the difference in...
3. Sickle-cell disease is a genetic condition caused by an autosomal recessive allele which al- fects one in every 500 African American children born in the U.S. One in every ten African Americans is a carrier for the recessive allels. Although sickle cell disease is caused by a single human gene, it is expressed through many different effects throughout the body. The presence of a recessive sickle-cell allele in humans causes the red blood cells to produce abnormal hemoglobin protein...
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