An action potential may be initiated in a neuron when [SELECT ONE "antagonist", "a neurotransmitter", "nerve impulse"] binds to a [SELECT ONE "ligand-gated", "open", "Na+/K+"] ion channel that serves as a [ SELECT ONE "receptor", "channel", "ligand"]
Action potential may be initiated in a neuron when a neurotransmitter binds to a ligand gated ion channel that serves as a receptor.
Explanation- ion channel receptors are also called as cell surface receptors,they enclose ion selective channels
Now neurotransmitter for example acetyl choline can act as agonist on nicotinic receptors which are ligand gated ion channels.
They bind to the receptors which results into opening of ion channels and causes depolarization/hyperpolarization or changes ionic compostion in cytosol.
An action potential may be initiated in a neuron when [SELECT ONE "antagonist", "a neurotransmitter", "nerve...
You are studying a ligand-gated ion channel. The ligand is a neurotransmitter. Upon binding the neurotransmitter, the ion channel opens and Na+ flows into the cell. The receptor is found on the dendrites of frog neurons. You are going to use one of the patch-clamp variations to study the effect of (1) the neurotransmitter and (2) second (and separately) the effect of an antagonist. Explain the patch-clamp technique variation you would use and why. Explain how you will study the...
Two neurons, A and B, synapse onto a third neuron, C. If neurotransmitter from neuron A opens ligand-gated channels permeable to sodium (Na) ions, and neurotransmitter from neuron B opens ligand-gated chloride (CI") channels, which of the following statements is true? Hint: Drawing a simple diagram may help visualize this scenario. Select one: a. An action potential in neuron A causes a depolarizing EPSP in neuron B. b. An action potential in neuron B causes a depolarizing EPSP in neuron...
2. Neuron during an action potential: a. What triggers the first action potential (which ion)? b. What is the typical threshold potential of a neuron? c. The calculated equilibrium potential of Na+ (EN) is approx. +60mV (calculated). Explain how this is related to the rising phase of an action potential (depolarization). d. The calculated equilibrium potential of K+ (EK) is approx. -90mV. Explain how this is related to the falling phase (repolarization). e. Direction of Nation movement (influx/efflux). f. Direction...
1. What channels or carriers are NOT found at the axon to the axon terminal? Select one: a. Na+ leaky channels b. Cl- gated channels c. Na+ gated channels d. Na+-K+ ATPase e. None of the above 2. What is TRUE about action potential in the neuron? There may be more than one answer. Select one or more: a. At resting membrane potential (-70mV), the inactivation gate of the Na+ channel is closed while the activation gate is opened. b....
Question 4 2 pts During and action potential, sodium (Na+) rushes into the cell causing of the cell. Then sodium channels close and potassium (K+) rushes out of the cell, causing of the cell. However, the potassium overshoots and causes Question 5 2 pts During the refractory period, the pumps Na+ ions out of the cell and K+ions into the cell, re-establishing the resting membrane potential and concentration gradient. Serotonin Acetylcholine Glutamate Endorphins Barbiturates GABA Dopamine Cocaine Sodium Potassium Calcium...
During the propagation of an action potential, what would be the effect of a mutation in the voltage-gated Na+-channels that does not allow “inactivation” phase to occur, such that these channels go directly from open to closed conformations? a) The neuron with the mutant Na+ channels will start letting in calcium ions and generate a calcium-based action potential that is stronger than the sodium-based action potential. b) The neuron with the mutant Na+ channel will exhibit a reverse electrochemical gradient...
5. Did you notice that during the action potential the neuron membrane potential reaches -90mV and stops? How/why does it stop at -90mV? Why doesn't it get more negative than -90mV? Hint: When the voltage-gated K+ channels are open on a neuron, there are so many voltage- gated K+ channels open that in reality you can think of the cell as being only permeable to K+. It's the main ion moving. Based on this and what we talked about on...
Please fill in the blank. When an action potential moves to a nerve cell’s terminals, ------ ions enter from the extracellular environment through gated channels to promote vesicle movement. ------ are chemicals responsible for the movement of a single across a synapse between two adjacent nerve cells. Regarding heterotrimeric G protein, the ------- subunit binds to and stimulates adenylyl cyclase (AC). In heterotrimeric G proteins, the ------- and ------- subunits(s) stimulate phospholipase C. The a-subunit of a heterotrimeric G protein...
Ldlicu upon 16 What is the difference between a graded potential and an action potential? Where would a praded potential occur in the neuron? An action potential? 16. The most widely used inhibitory neurotransmitter is This neurotransmitter opens up ion channels in the postsynaptic membrane. Ions rush (in/out) and bring the cell (closer to/further from) threshold level. 17. Label the following diagram with these terms: depolarization, repolarization, hyperpolarization, Na gates open, Na' gates closed, K gates open, K' gates closed,...
What is a resting potential? Is it positive or negative? The resting potential is mainly due to the main _____-charged large molecules stuck inside the neuron. The Na+/K+ pump pushes Na+ _____ of the cell and K+ ____ of the cell (in or out for each ion) Where is K+ concentrated, inside or outside of the neuron? Where is Na+ concentrated, inside or outside of the neuron? The action potential starts with an rise in membrane voltage. This is due...