Question

32. Which of the following lipids contain a carbohydrate as part of it's structure:

A. Cerebroside

B. Ganglioside

C. Ceramide

D. All of the above

E. A and B only

33. Which of the following is a ketone body?

A. Succinate

B. B-hydroxyacetate

C. Acetoacetate

D. Acetyl CoA

E. Alpha-Ketoglutarate

35. Which of the following is true about the regulation of fatty acid oxidation?

A. Acetyl CoA inhibits thiolase

B. Increased consumption of glucose increases fatty acid oxidation

C. Carnitine acyl transferase I is activated by malonyl CoA

D. Carnitine acyl transferase I is inhibited by acetyl CoA

E. High levels of NADH activate B- hydroxyl CoA dehydrogenase

36. Which of the following is true about reactions involving reduced glutathione (GSH)?

A. NADPH is required to convert GSH to the reduced form (GSSG)

B. In RBC's it oxidizes the cysteines of Hemoglobin

C. It is composed of glutamic acid, glycine, and cysteine

D. It oxidizes water to hydrogen peroxide

E. It is an inhibitor of glutathione peroxidase

37. Oxidation of a fatty acid with an odd number of carbons will result in acetyl CoA and:

A. Malonyl CoA

B. Glycerol

C. Propionyl CoA

D. NADPH

E. Coenzyme Q10

38. Phosphatidic acid is a precursor of all of the following except:

A. Sphingomyelin

B. Triacylglycerol

C. Phosphatidyl serine

D. Phosphatidyl ethanolamine

E. Phosphatidyl choline

39. Which of the following is an essential fatty acid?

A. Palmitic Acid

B. Oleic Acid

C. Myristic Acid

D. Arachidonic Acid

E. Linoleic Acid

40. Select the true statement/s about the cytochrome P-450 system:

A. It catalyzes the hydroxylation of steroids and many drugs

B. It may convert potential carcinogens into a chemically reactive form

C. It requires NADH for full activity

D. A, B, and C are true

E. A and B only are true

41. Bile acid resins (cholestyramine) lower the level of cholesterol by:

A. Converting cholesterol to cholesteryl esters

B. Decreasing the expression of LDL receptors

C. Inhibiting the reabsorption of glyocholate and taurocholate from the intestine

D. Stimulating the degradation of glycocholate and taurocholate

E. Inhibiting the activity of HMG-CoA reductase

Answer 1

Answer 32: A and B only

Cerebroside: contain single sugar unit that is carbohydrate

Ganglioside: contain sugar chain that is carbohydrates

Ceramide: it contain sphingosine (phospholipid) and fatty acids

Answer 33: C: Acetoacetate

Acetone, D hydroxybutyrate, Acetoacetate are ketone bodies.

Acetyl CoA is converted into ketone bodies.

Succinate is metabolite in the glyoxylate cycle.

Alpha-Ketoglutarate is ketone derivative of glutaric acid

Answer 35: A. Acetyl CoA inhibits thiolase

Acetyl CoA is common product form by glucose, amino acids and fatty acids.

Malonyl CoA inhibits the Carnitine acyl transferase I

acetyl CoA is cofactor take part in biochemical reaction.

Answer 37: C. Propionyl CoA

Two molecules of acetyl CoA are form in case of even number of even number of fatty acid oxidation.

Answer 39: Linoleic Acid

Palmitic Acid and Myristic Acid, Arachidonic Acid are non essential fatty acid.

Essential: those fatty acids can not be synthesized by body