Describe the process by which a cell would display an intracellular (virus) on MHC, including how the pathogen gets in the cell and eventually gets placed on the correct MHC (tell me the class) and displayed on the cell surface.
Jntracellular peptides or virus in cells undergoes fragmentation via proteasomes. Proteasomes are structures that are responsible for degradation of proteins. When the peptide fragments are produced, they bind to TAP, a type of ABC transporter on the cytoplasmic side. With the help of ATP hydrolysis, the peptide is transported from the cytoplasm to the inside of ER lumen. The selected peptide is then expressed over MHC I which is then transported to golgi complex , then to the outside of cell via secretory vesicles where they interact with T lymphocytes
Describe the process by which a cell would display an intracellular (virus) on MHC, including how...
Describe how you would use intracellular flow cytometry to see which of your 3 cell lines produce IL-17 when stimulated with IL-23, and what you would see with positive or negative results.
D 1. FO Based on your knowledge of MHC I and II, predict which cell type would be MOST likely not to express detectable MHC I. s Intestinal epithelial cells Macrophages Basophils Erythrocytes Dendritic cells D 2. In MHC Class I, internal proteins/antigens are digested by the Peptides are loaded onto MHC Class I in the ER. Then exported to the cell surface. lysosome proteasome phagosome E phagolysosome none of the above
Adaptive Immunity: Second Line of Defense—Cellular Defenses The T-cell receptors and CD4 and CD8 molecules interact with major histocompatibility complex (MHC) proteins. MHC proteins are found on most cells of the body. There are two variations, or classes, of MHC proteins. MHC class I is expressed on the surface of most cells of the body such as skin cells, liver cells, and others. Should a cell become infected with a virus, viral antigens are processed in the cells and expressed...
Pls help me fill in the blanks sir/maam T cells mature in the thymus gland in response to that is secreted by the thymus gland. When a T cell leaves the thymus it has a unique These T cells are not able to recognize foreign invaders called _without help. The invader has to be presented to the T cell in a specific way by an __ protein. Immunity mediated by T cells and Tc cells is referred to as _immunity....
cellular respiration 3. Next, let's describe in detail how the majority of ATP in the cell is produced: a. How is the energy obtained from the breakdown of glucose transferred into a form that can do work? Be sure to tell me what proteins or other moving parts are involved (3 pt). b. This process is driven by highly electro-negative oxygen acting as a cellular
Question 15 (2 points) MHC class I interacts primarily to which subclass of T cell Question 15 options: A) CD8 positive B) CD3 positive C) CD4 positive D) CD2 positive Question 16 (2 points) T helper cells generally can stimulate B cells to differentiate into: Question 16 options: A) NK cells and cytotoxic T cells B) memory cells and plasma cells C) anergic cells and effector cells D) NK cells and memory cells E) anergic cells and memory cells Question...
33.) Which of the following would be classified as barriers of the innate defenses? a.) activation of the complement system b.) release of histamine c.) washing action of tears, skin acidity, mucus, and saliva d.) inflammation 34.) What is the role of interferon in defense against disease? a.) protects cells that have not yet been infected by viruses b.) protects cells that have not yet been infected by bacteria c.) activates the complement mechanism d.) activates the inflammatory process 35.)...
3) Describe the process by which fluid (such as blood) can be removed from the pelvic cavity of a female, using the correct anatomical terminology. 4) How many segmental arteries does each kidney usually have? 5) Describe the three major areas of the pelvis through which nerves and blood vessels enter and leave (not including the continuation of structures from the abdominal cavity). 6) Describe the deficits that would result from complete loss of function of the pudendal nerve (i.e....
List and describe at least 5 different ways in which genetic diversity in immunoglobulins arise. Describe three ways in which complement acts to protect the host during infection. Identify specific molecules/ convertases and their contributions to the immune response. Complement activation can occur via the classical, alternative or lectin pathway. Identify which pathway you would expect to be activated in a patient that had a seasonal flu shot in October 2019. Streptococcus pneumoniae Influenza virus Escherichia coli Present a scenario...
Which of these is the best description of a virus? Multiple Choice 0 a member of the kingdom Virusae 0 the smallest bacteria known 0 a noncellular living organism 0 chemical complexes of RNA or DNA protected by a protein shell Which of the following is a characteristic of all living things? Multiple Choice 0 All living things are made up of multiple cells. 0 All living things breathe. 0 All living things maintain a constant internal environment. 0 All...