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What is the ApoE gene and which genotypes are associated with a higher disease risk for...

What is the ApoE gene and which genotypes are associated with a higher disease risk for CVD and Alzheimer's?

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The APOE gene provides instructions for making a protein called apolipoprotein E.This protein combines with fats(lipids) in the body to form molecules called lipoproteins.Lipoproteins are responsible for packaging cholesterol and other fats and carrying them through the bloodstream.Maintaining normal levels of cholesterol is essential for the prevention of disorders that affect the heart and blood vessesls(cardiovascular diseases), including heart attack and stroke.

APOE e3 is associated with higher risk of Cardiovascular diseaseand APOE e4 is associated with Alzheimer's disease.

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