A drug derived from the neem tree (Gedunin) was found, it inhibited cell division and induced apoptosis in a human carcinoma cell line.
Why would it be “good” for Gedunin to induce apoptosis in the cancer cells?
A drug derived from the neem tree (Gedunin) was found, it inhibited cell division and induced...
Depletion of cholesterol in the cell membrane using a drug (mevastatin) has been associated with apoptosis in cancer cells. a. What effect would cholesterol depletion have on the integrity of lipid rafts in the membrane? b. Researchers found that FAS death receptor was activated in cholesterol depleted cancer cells. Explain how activation of this receptor activates killer caspases. c. When a caspase is converted from its inactive to its active form there are changes in the primary and tertiary structure...
A reserach is observing cell division in cells derived from a diploid organism. She traps the cell at the end of mitotic prophase and counts a total of 108 chromatids Based on this count, how many chromosomes would be contained in a normal gamete for this organism? PS: the answer is not 54 I have already tried this answer.
You want to create an anti-cancer drug that destabilizes microtubules, hoping to prevent cell division in the cancer cell line that you are studying. Which of the following drugs would enhance microtubule shrinkage and, therefore, utilize this mechanism of action? Answers A-D A a drug that inhibits GTP hydrolysis by the B-subunit in the GTP cap O B a drug that increases the ability of a tubulin dimer to bind to y-tubulin of the centrosome с a drug that increases...
why iis so difficult to stop a drug that will stop cell division only tumor cells?
The anticancer drug paclitaxel (Taxol), derived from the Pacific Yew, has many effects on mitosis. One of its most powerful effects is that it prevents disassembly of the mitotic spindle, which prevents spindle fibers from shortening. Which phase of mitosis would this directly affect? Why would this stop cell division overall and lead to cell death? 4 Your patient has a severe infection, and you want to get an antibiotic into his system as quickly as possible. You have two...
QUESTION 6 An organism has 2 pairs of chromosomes 1 and 2. A certain female from this species was found with chromosome 1 has blue gene on one pair and orange gene on the other. Number 2chromosomes both have the short gene. As cells in her ovaries undergo meiosis, which of the following combinations of genes and chromosomes will her eggs have? A) only blue short gene eggs OB) only orange short gene eggs OC) one half blue short and...
If a hypothetical drug prevents actin from working properly, how would cell division be affected? DNA synthesis would not occur cell elongation during anaphase would not occur spindle formation would not occur spindle attachment to kinetochores would not occur cleavage furrow formation and cytokinesis would not occur
BIOS 1705. At-Home Worksheet Cell Division and Cancer (10 points) Name: Below are pictures of cells in the various phases of mitosis and the cell cycle from plants for Activity 1 and animal cells for Activity 2. They are in either interphase, prophase, metaphash, anaphase, telophase or cytokinesis. On the line under the picture indicate which phase each cell is in Activity 1 Mitosis in Plant cells -- Onion Root Tip Add-ins Media Links Activity 2 Observing Mitosis in Animal...
Recent studies support the potential of a drug that is derived from the metal iridium to effectively treat cancer. This experimental drug, Drug ZL105, has not been tested for efficacy and toxicity. Imagine that you are the one responsible for approving or denying the use of this drug within the United States. Your job is to propose the testing that is needed for this drug to be determined as safe and effective for the treatment of cancer in humans. In...
You are a researcher studying the potential cardiac toxicity of a new drug that your company is developing. You have three potential in vitro models available to you: a 3D model of the human heart (cardiac spheroids) using primary cells as the source for cardiomyocytes, culture of embyronic stem cell-derived cardiomyocytes from rats, or the Langendorff isolated heart preparation. Choose one of these models that you would use and explain why. Include in your reasoning at least one pro and...