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Which of the following are primary mechanisms through which microorganisms evade antimicrobial drugs? To be marked...

Which of the following are primary mechanisms through which microorganisms evade antimicrobial drugs? To be marked correct, you'll need to select all applicable statements, as there may be more than one correct answer.

Drug target alterations
Reducing drug concentration inside of the cell
Drug inactivation
Decreasing intracellular drug solubility
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  • Drug target alterations
  • Reducing drug concentration inside of the cell
  • Drug inactivation

Microorganisms may alter protein which are the target of drug. They may inactivate or reduce the concentration of drug by enzymatic degradation. Also, they may change the membrane permeability for the drug.

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