Question

1.Energy stored in the covalent bonds of a molecule of C₆H₁₂O₆ would best be described as? Why wouldn't it be kinetic energy?

2.Reaction (1) is     A + B <--> C + H₂O.     It is endergonic with a ΔG = 6.3 kcal/mol

Reaction (2) is      ATP + H₂O <--> ADP + P_i .   It is exergonic with a ΔG = -7.3 kcal/mol

If these two reactions are coupled, what is the overall free energy for the reaction?

3.For enzyme catalzyed reactions, what is the "transition" state?

Answer 1

1. The energy stored in the covalent bonds of a molecule of glucose is best described as potential energy. This is also called as chemical energy.

This cannot be called as kinetic energy as the molecules are not in motion. The energy in the bonds hold the atoms together. So, it will be potential energy.

2. The net energy we calculate by using simple mathematics.

+6.3+ (-7.3) = -1 kcal/mol

The overall free energy of the reaction will be -1 kcal/mol.

3. Transition state is the state in which the enzyme is bound to the substrate. In this state the substrate is bound to the enzyme and substrate is converted to products later.