Question

Part 1: what might cause lysosomes to change their location in the cell so they could fuse with the plasma membrane.

Part 2: 2-hydroxyoleic acid can increase the activity of sphingomyelin synthase causing the cells to stop dividing and initiate apoptosis! The FAS death receptor (UNIT3) is localized to lipid rafts. Explain why 2-hydroxyloleic acid treatment could cause a cancer cell to initiate apoptosis.

Answer 1

1. Lysosome, a subcellular organel, contains a wide scope of hydrolytic compounds (corrosive hydrolases) that separate macromolecules, for example, nucleic acids, proteins, and polysaccharides. These proteins are just dynamic in the acidic inside setting of the lysosome.

Lysosomes start from the layer of the trans-Golgi arrange, a Golgi complex area.Then the lysosomes combine with film vesicles coming about because of one of three procedures: endocytosis, autophagocytosis, and phagocytosis. Extracellular macromolecules are taken up into the phone in endocytosis to frame film bound vesicles called endosomes melding with lysosomes. Autophagocytosis is the technique for expelling antiquated organs and breaking down cell parts from a phone; they are encompassed by inward layers that circuit with lysosomes afterwards. Phagocytosis is performed by particular cells (for example macrophages) that include enormous extracellular particles, for example, dead cells or outside trespassers (for example microbes), focusing on them for lysosomal debasement.

Due to any of these three causes lysosome fused with plasma membrane and discharges these waste outside the cell through exocytosis. Albeit a considerable lot of the lysosomal absorption items, for example, amino acids and nucleotides, are reused back to the cell for use in new cell part combination.