Please explain the immune activation for Trypansoma cruzi parasite.
Chagas disease is named after the Brazilian physician Carlos Chagas , who discovered the disease in 1909. It is caused by the parasite Trypanosoma cruzi, which is transmitted to animals and people by insect vectors and is found only in the Americas.
THE IMMUNE ACTIVATION FOR Trypanosoma cruzi parasite basically involves the six different types of methods
1.Complement inactivation of the immune proteins
2.Mammalian nucleated cell phagocyte the parasite and it gets escape into cytosol causing the problem to cell
3.B-cells activation antibodies
4.Delayed immune response of CD8+ T CELLS
5.Macrophages - immunoactivation by TLR2 ,TLR7 , TLR (toll like receptors)
6.Dendritic cells- immunoactivation by TLR 7 and TLR 9
Investigate the different parts of the human immune system and explain which cells/products of innate and adaptive immunity are responsible for recognizing antigens on the surface of T. brucei and clearing the parasite. What would happen if T. brucei suddenly loss the ability to undergo antigenic variation? If researchers developed a drug that could prevent T. brucei from undergoing antigenic variation, do you think it could be successful in eradicating African Sleeping Sickness? Would the drug have to be administered...
5) Schistoma and Trypanosom cruzi are parasites that are capable of evading the immune system. However they use different mechanisms of evasion. Discuss how they do so and make comparisons with each other.
You are interested in examining T cell activation during an immune response in vivo. You are given: anti-Bcell, anti-T cell, anti-CD4, anti-CD8, and anti-IFNg antibodies. Draw a simple gating strategy (plots) to show how you would measure T cell activation in a spleen. only draw ONE gate per plot draw cells as dots or large circles (or peaks for one parameter plots) draw an arrow to the final gate where you would expect to see protein expression differences for activated...
Please explain in detail. What two sub units are in charge of the phospholipase C activation and what does an active phospholipase C do?
What is the activation energy for the reaction B -> A in the following diagram? PLEASE EXPLAIN! 1) (1.5 pt) What is the activation energy for the reaction B A in the following diagram? A)A B B C) C DID E) E En Reaction Coordinate
With the weather changing and flu season coming up, please explain how your immune system protects you, factors that diminish its effectiveness, and what you can do to boost its effectiveness.
explain mechanical barriers for immune responses
PLEASE EXPLAIN IN DETAIL QUESTION 11 The activation energy for the reaction associated with the figure shown is A E Reaction coordinate a. D minusA . B minus A C. D minusC O d. C minus E e. D minusE
1. Explain the difference between activation of g-protein coupled recepetor activation and direct gene activation. A. Which one happens faster? B. Which one lasts longer?
1/ a/ Explain how each of these relationships may affect the distribution of animals: predator-prey, parasite-host, competition, mutualism, commensalism. b/ Outline the evolutionary effects of predator-prey relationships on the characteristics of both the prey and the predator.