What are the possible outcomes of phosphorylation of an effector protein in a signaling pathway?
What are the possible outcomes of phosphorylation of an effector protein in a signaling pathway?
4) A signaling pathway proceeds through three protein kinases that are sequentially activated by phosphorylation. In one case, the kinases are held in a signaling complex by a scaffold protein. In the other, the kinases are freely diffusing. Discuss the properties of these two types of organization in terms of the signal amplification, speed, and potential cross talk between signaling pathways. (10 Points)
Activity 4. Receptor signaling pathway A model of a G protein receptor signaling pathway is represented below. Activation of the signaling pathway results in a cell secreting a neurotransmitter through exocytosis. Activated - Activated adenylyl receptor cyclase GTP АТР CAMP Active G protein Protein- kinase A Inactive Active Protein targets Phosphate group A. Different steps in a signaling pathway can amplify the initial signal of one ligand binding to one receptor. Choose one step in the pathway below that results...
Describe how a single protein in the tyrosine kinase signaling pathway possesses all the protein functions that characterize signal transduction.
Which of the following is NOT an intracellular signaling protein activated by an RTK pathway? Akt Raf Erk adenylyl cyclase
You are studying a signal transduction pathway. Activation of your pathway results in activation of transcription of a gene that you are studying. In addition, activation of the signal transduction pathway results in phosphorylation of a number of effector proteins. Which of the following is most likely an effector protein of your signal transduction pathway that regulates transcription of your gene? A. An activator protein B. A coactivator protein C. A HAT D. A basal factor E. RNAPII
I would prefer if you described the PERK signaling pathway out
of the 3. Thanks! The figure might help.
Describe in detail 1 (out of the 3) ER stress signaling pathways. Include all of the signaling components of the pathway [ligand, receptor, secondary signaling molecule(s), effector(s), cellular response, etc.) and their specific function. m BiP BIP BiP PERK IRE1 ATF6 ER 33333333 Cytosol Translocation to Golgl, cleavage by S1P and S2P Constant degradation elF2a Nrf2 ) Keap! XBP1s ATFO Dissociation...
QUESTION 18 Following activation of a mitogenic signaling pathway, which of these events occur to promote cell division? a. Dephosphorylation of Retinoblastoma protein. b. Increased expression of p21. c. Phosphorylation of Myc. d. Inhibition of new protein synthesis. 1 points QUESTION 19 The slow rise of S cyclin levels throughout G1 phase is due to ___________, and the abrupt decrease is caused by ___________. a. import; export b. synthesis; mitosis c. transcription; proteolysis d. phosphorylation; translation
Like the Ras protein itself, the various components of the Ras signaling pathway are changed in cancer cells. What might be the biochemical consequence of mutations in the genes coding for (a) Raf and (b) MAP kinase that result in rapid cell division?
Find the below for Donepezil: Primary and secondary messenger: Intracellular signaling proteins involved Target proteins (effector molecules): Form of protein regulation (phosphorylation, acetylation, etc.):
Which of the following is the best option to reduce signaling that is regulated by a PROTEIN hormone? Mutate the enzymes involved in the protein hormone synthesis pathway to block their function. Mutate the enzymes involved in the protein hormone synthesis pathway to increase their reactivity. Mutate the protein hormone gene to make it non-functional. Mutate the protein hormone gene to make it more highly expressed. b What of the following are mechanisms to turn a signaling pathway OFF? (CIRCLE...