1. list 2 specific polypeptides found in the human body that are not hemoglobin 2. what...
1. list 2 specific polypeptides found in the human
body that are not hemoglobin
2. what is the molecular basis for sickle cell anemia?
Homework Answers
Ans:-1)
2 specific polypeptides found in the human body are :- insulin and growth harmones
Ans:-2) molecular basis for sickle cell anemia :-
There occur A-to -T point mutations in the beta-globin gene which results in abnormal hemoglobin S(HbS) .This abnormal hemoglobin S polymerised in the deoxygenated state and results in suckling of red blood cells.
Add Answer to:
1. list 2 specific polypeptides found in the human
body that are not hemoglobin
2. what...
1.Hemoglobin is a complex protein that contains four polypeptide chains. The normal hemoglobin found in adults...
1.Hemoglobin is a complex protein that contains four polypeptide chains. The normal hemoglobin found in adults –called adult hemoglobin –consists of two alpha and two beta polypeptide chains, which are encoded by different loci. Sickle-cell hemoglobin, which causes sickle-cell anemia, arises from a mutation in the beta chain of adult hemoglobin. Adult hemoglobin and sickle-cell hemoglobindiffer in a single amino acid: the sixth amino acid from one end in adult hemoglobin is glutamic acid, whereas sickle-cell hemoglobin has valine at...
Compare the hemoglobin sequences on the following page and then answer parts A-C. Part A) Is...
Compare the hemoglobin sequences on the following page and then answer parts A-C. Part A) Is there any difference in the amino acid sequence of the alpha subunits in normal and sickle cell hemoglobin? If yes, which amino acids are different? (Count the amino acids by their order in the sequence – first, second, third...) What amino acid or acids are in the normal alpha subunit and what amino acid or acids are in the sickle cell amino acid? Part...
Sickle-cell anemia is caused by a single point mutation in the hemoglobin of human red blood...
Sickle-cell anemia is caused by a single point mutation in the hemoglobin of human red blood cells. It is a recessive gene. People who have sickle cell anemia are homozygous recessive and suffer terribly from this disorder. Now I have stated in lecture that mutations are neither good nor bad. Rather it depends on how the mutation effects the survival of the species. If the mutation harms the survival of the species it is bad, if it helps the survival...
Sickle-cell anemia is caused by a single point mutation in the hemoglobin of human red blood cells. It is a recessive gene. People who have sickle cell anemia are homozygous recessive and suffer terribly from this disorde
Sickle-cell anemia is caused by a single point mutation in the hemoglobin of human red blood cells. It is a recessive gene. People who have sickle cell anemia are homozygous recessive and suffer terribly from this disorder. Now I have stated in lecture that mutations are neither good nor bad. Rather it depends on how the mutation effects the survival of the species. If the mutation harms the survival of the species it is bad, if it helps the survival...
Case 8 Hemoglobin, the Oxygen Carrier Focus concept A mutation in the gene for hemoglobin results...
Case 8 Hemoglobin, the Oxygen Carrier Focus concept A mutation in the gene for hemoglobin results in an altered protein responsible for the disease sickle cell anemia. An understanding of the biochemistry of the disease may suggest possible treatments Prerequisite Hemoglobin structure and function concepts Background Normal adult hemoglobin is called Hemoglobin A (Hb A). Ninety-eight percent ofaduk hemoglobin is Hb A and 2% is Hb A. There are other forms of hemoglobin. For example, the deve loping fetus has...
In plain language, describe what the oxygen-hemoglobin dissociation curve shows. Under normal conditions, the curve can...
In plain language, describe what the oxygen-hemoglobin
dissociation curve shows. Under normal conditions, the curve can
shift to the right and left. A right shift can be induced by
increased temperature and lower pH among other things. Describe
what a right shift means in terms of hemoglobin’s relationship to
oxygen. In your answer, be sure you address what is actually
happening at the level of the protein (hemoglobin is a protein).
Discuss what types of molecular interactions that can cause...
Table 2. Results of blood and hemoglobin tests for case study. Subject Blood type (phenotype) Hemoglobin...
Table 2. Results of blood and hemoglobin tests for case
study.
Subject
Blood type (phenotype)
Hemoglobin genotype
Mother
A+
HbAS
Baby
A+
HbAA
Male Subject
O-
HbAS
Based on your results shown in Table 2, can you exclude the
possibility of paternity? Cite the specific results
that allow you to make this claim
What are ALL of the potential genotypes for each subject based
on blood type?
Define the difference between genotype and phenotype.
Supplementary Information A gene is a...
How many pairs of chromosomes are there in a normal human body cell? 1 23 4...
How many pairs of chromosomes are there in a normal human body cell? 1 23 4 billions. Who wrote On the Origin of Species by Means of Natural Selection, or The Preservation of Favored Races in the Struggle for Life, the classic work providing the foundation for the development of modern evolutionary thought? William Darwin. Charles Darwin. Thomas Darwin. Robert Darwin. According to proponents of "natural theology," an adapted organism is like: the British Parliament, with the head ruling like...
1.All cells in a human body undergo the process of meiosis. True False 2. Most cells...
1.All cells in a human body undergo the process of meiosis. True False 2. Most cells in the human body contain 46 chromosomes. True False 3. The chances that any two siblings will be genetically identical is astronomically small. True False 4. Each time protein synthesis occurs; all of the DNA of a cell is copied. True False RNA creation occurs in the nucleus of a cell; protein synthesis occurs on the ribosomes. True False 6. Tay-Sachs syndrome is a...
Patients with Anemia present with specific assessment character. Please describe! 1. What specific laboratory values will...
Patients with Anemia present with specific assessment character. Please describe! 1. What specific laboratory values will you include in your objective assessment of persons with anemia.? 2.What is sickle cell anemia , and what are the clinical manifestation? What complications can occur. 3. What is a Blood transfusion and what is the RN responsible for. 4. What are the clinical manifestations of a transfusion reaction. 5. What is hemochroatosis? 6. What is acute leukemia, clinical manifestations, Lab values. 7. What...
Compare the hemoglobin sequences on the following page and then answer parts A-C. Part A) Is there any difference in the amino acid sequence of the alpha subunits in normal and sickle cell hemoglobin? If yes, which amino acids are different? (Count the amino acids by their order in the sequence – first, second, third...) What amino acid or acids are in the normal alpha subunit and what amino acid or acids are in the sickle cell amino acid? Part...
Case 8 Hemoglobin, the Oxygen Carrier Focus concept A mutation in the gene for hemoglobin results in an altered protein responsible for the disease sickle cell anemia. An understanding of the biochemistry of the disease may suggest possible treatments Prerequisite Hemoglobin structure and function concepts Background Normal adult hemoglobin is called Hemoglobin A (Hb A). Ninety-eight percent ofaduk hemoglobin is Hb A and 2% is Hb A. There are other forms of hemoglobin. For example, the deve loping fetus has...
In plain language, describe what the oxygen-hemoglobin
dissociation curve shows. Under normal conditions, the curve can
shift to the right and left. A right shift can be induced by
increased temperature and lower pH among other things. Describe
what a right shift means in terms of hemoglobin’s relationship to
oxygen. In your answer, be sure you address what is actually
happening at the level of the protein (hemoglobin is a protein).
Discuss what types of molecular interactions that can cause...
Table 2. Results of blood and hemoglobin tests for case
study.
Subject
Blood type (phenotype)
Hemoglobin genotype
Mother
A+
HbAS
Baby
A+
HbAA
Male Subject
O-
HbAS
Based on your results shown in Table 2, can you exclude the
possibility of paternity? Cite the specific results
that allow you to make this claim
What are ALL of the potential genotypes for each subject based
on blood type?
Define the difference between genotype and phenotype.
Supplementary Information A gene is a...
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