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What evidence would you suggest to support that organisms that use the acetyl-CoA pathway are anaerobics?

What evidence would you suggest to support that organisms that use the acetyl-CoA pathway are anaerobics?

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Methanogens are types of organisms, classified as archaea, that exhibit the ability to produce methane as a metabolic byproduct. Methanogens present in non aerobic conditions, are able to use carbon dioxide as a source of carbon for growth. In addition, the carbon dioxide is used as an electron acceptor in the production of methane. Methanogens are able to utilize the acetyl-CoA pathway to fix carbon dioxide.

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What evidence would you suggest to support that organisms that use the acetyl-CoA pathway are anaerobics?
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